(Q27932524)

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Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity

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scholarly article

1 reference

Europe PubMed Central

1 July 2017

Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity (English)

1 reference

Europe PubMed Central

1 July 2017

0 references

Saccharomyces cerevisiae

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NAD-dependent histone deacetylase SIR2 YDL042C

1 reference

GOA release 2020-03-11

author name string

Christopher M Armstrong

1

1 reference

Europe PubMed Central

1 July 2017

Matt Kaeberlein

2

1 reference

Europe PubMed Central

1 July 2017

Shin Ichiro Imai

3

1 reference

Europe PubMed Central

1 July 2017

Leonard Guarente

4

1 reference

Europe PubMed Central

1 July 2017

language of work or name

0 references

publication date

1 April 2002

1 reference

Europe PubMed Central

1 July 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

1 July 2017

13

1 reference

Europe PubMed Central

1 July 2017

1427-1438

1 reference

Europe PubMed Central

1 July 2017

4

1 reference

Europe PubMed Central

1 July 2017

Crystal structure of a SIR2 homolog-NAD complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

20 March 2017

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

Transcriptional silencing of Ty1 elements in the RDN1 locus of yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

An unusual form of transcriptional silencing in yeast ribosomal DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: a molecular model for the formation of heterochromatin in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

7 April 2017

Coupling of histone deacetylation to NAD breakdown by the yeast silencing protein Sir2: Evidence for acetyl transfer from substrate to an NAD breakdown product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

25 years after the nucleosome model: chromatin modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

Locus specificity determinants in the multifunctional yeast silencing protein Sir2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

The conserved core of a human SIR2 homologue functions in yeast silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

29 September 2017

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

2 June 2018

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

2 June 2018

CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis i

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=102280

27 November 2018

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/11950950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11950950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.01-10-0482

1 reference

Europe PubMed Central

1 July 2017

0 references

1 reference

Europe PubMed Central

1 July 2017

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