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Cer1p functions as a molecular chaperone in the endoplasmic reticulum of Saccharomyces cerevisiae
scientific article
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
10409721
retrieved
1 December 2016
title
Cer1p functions as a molecular chaperone in the endoplasmic reticulum of Saccharomyces cerevisiae
(English)
1 reference
stated in
PubMed
PubMed ID
10409721
retrieved
1 December 2016
main subject
endoplasmic reticulum
0 references
Saccharomyces cerevisiae
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molecular chaperones
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Hsp70 family chaperone LHS1 YKL073W
1 reference
stated in
GOA release 2020-03-11
author name string
T G Hamilton
series ordinal
1
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T B Norris
series ordinal
2
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P R Tsuruda
series ordinal
3
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G C Flynn
series ordinal
4
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language of work or name
English
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publication date
August 1999
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published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
10409721
retrieved
1 December 2016
volume
19
0 references
issue
8
0 references
page(s)
5298-307
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cites work
SSI1 encodes a novel Hsp70 of the Saccharomyces cerevisiae endoplasmic reticulum.
1 reference
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PubMed Central
reference URL
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20 March 2017
A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors
1 reference
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PubMed Central
reference URL
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20 March 2017
A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae
1 reference
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PubMed Central
reference URL
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retrieved
20 March 2017
Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
20 March 2017
A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
20 March 2017
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
KAR2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
The signal recognition particle in S. cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
Effect of constitutive 70-kDa heat shock protein polymerization on its interaction with protein substrate
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
Kinetics of molecular chaperone action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
20 March 2017
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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20 March 2017
A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
7 April 2017
Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
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7 April 2017
Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
7 April 2017
The lumenal domain of Sec63p stimulates the ATPase activity of BiP and mediates BiP recruitment to the translocon in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Signal sequences specify the targeting route to the endoplasmic reticulum membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Reconstitution of protein translocation from solubilized yeast membranes reveals topologically distinct roles for BiP and cytosolic Hsc70.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Eukaryotic DnaJ homologs and the specificity of Hsp70 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Identification of the peptide binding domain of hsc70. 18-Kilodalton fragment located immediately after ATPase domain is sufficient for high affinity binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Ubiquitin-assisted dissection of protein transport across membranes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
Successive action of DnaK, DnaJ and GroEL along the pathway of chaperone-mediated protein folding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
29 September 2017
The Hsp70 homologue Lhs1p is involved in a novel function of the yeast endoplasmic reticulum, refolding and stabilization of heat-denatured protein aggregates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
Cloning and characterization of the Saccharomyces cerevisiae LYS7 gene: evidence for function outside of lysine biosynthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
Interconversion of three differentially modified and assembled forms of BiP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
Sec61p and BiP directly facilitate polypeptide translocation into the ER.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
2 June 2018
Negative regulation of FAR1 at the Start of the yeast cell cycle.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
27 November 2018
ATP-induced protein-Hsp70 complex dissociation requires K+ but not ATP hydrolysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84373
retrieved
27 November 2018
Peptide binding and release by proteins implicated as catalysts of protein assembly
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effect of nucleotides, peptides, and unfolded proteins on the self-association of the molecular chaperone HSC70
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cer1p, a novel Hsp70-related protein required for posttranslational endoplasmic reticulum translocation in yeast
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
BiP maintains the permeability barrier of the ER membrane by sealing the lumenal end of the translocon pore before and early in translocation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Formaldehyde in formaldehyde/agarose gel may be eliminated without affecting the electrophoretic separation of RNA molecules
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peptide-binding specificity of the molecular chaperone BiP
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/10409721
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.19.8.5298
0 references
PMCID
84373
0 references
PubMed ID
10409721
1 reference
stated in
PubMed
PubMed ID
10409721
retrieved
1 December 2016
ResearchGate publication ID
12889173
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