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An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation
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scholarly article
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stated in
PubMed
PubMed ID
12769863
retrieved
1 December 2016
title
An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation
(English)
1 reference
stated in
PubMed
PubMed ID
12769863
retrieved
1 December 2016
main subject
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0070478
Ski7p YOR076C
1 reference
stated in
GOA release 2020-03-11
ATP-dependent RNA helicase NAM7 YMR080C
1 reference
stated in
GOA release 2020-03-11
Exosome non-catalytic core subunit SKI6 YGR195W
1 reference
stated in
GOA release 2020-03-11
SKI complex RNA helicase subunit SKI2 YLR398C
1 reference
stated in
GOA release 2020-03-11
author
David Tollervey
series ordinal
2
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author name string
Philip Mitchell
series ordinal
1
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language of work or name
English
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publication date
May 2003
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published in
Molecular Cell
1 reference
stated in
PubMed
PubMed ID
12769863
retrieved
1 December 2016
volume
11
0 references
page(s)
1405-13
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issue
5
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cites work
Functions of the exosome in rRNA, snoRNA and snRNA synthesis
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of ribosomal RNA precursors by the exosome
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential component of the decapping enzyme required for normal rates of mRNA turnover
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast antiviral proteins Ski2p, Ski3p, and Ski8p exist as a complex in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
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7 January 2021
based on heuristic
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Computational modeling and experimental analysis of nonsense-mediated decay in yeast
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dob1p (Mtr4p) is a putative ATP-dependent RNA helicase required for the 3' end formation of 5.8S rRNA in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
mRNA decay enzymes: decappers conserved between yeast and mammals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site specific enzymatic cleavage of RNA
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
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inferred from DOI database lookup
An mRNA surveillance mechanism that eliminates transcripts lacking termination codons
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an additional gene required for eukaryotic nonsense mRNA turnover
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene products that promote mRNA turnover in Saccharomyces cerevisiae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The 3' end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
smg mutants affect the expression of alternatively spliced SR protein mRNAs in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Premature translational termination triggers mRNA decapping
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binary specification of nonsense codons by splicing and cytoplasmic translation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms and control of mRNA decapping in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exosome-mediated recognition and degradation of mRNAs lacking a termination codon
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional link between the mammalian exosome and mRNA decapping
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
based on heuristic
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Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900190-4
retrieved
7 January 2021
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inferred from DOI database lookup
Identifiers
DOI
10.1016/S1097-2765(03)00190-4
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5040813
OpenCitations bibliographic resource ID
5040813
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5040813
PubMed ID
12769863
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
5040813
ResearchGate publication ID
10740268
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