(Q27938024)

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Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

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scholarly article

1 reference

1 December 2016

Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein (English)

1 reference

1 December 2016

endoplasmic reticulum

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Saccharomyces cerevisiae

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Type I HSP40 co-chaperone YDJ1 YNL064C

1 reference

GOA release 2020-03-11

Type I HSP40 co-chaperone HLJ1 YMR161W

1 reference

GOA release 2020-03-11

E3 ubiquitin-protein ligase SSM4 YIL030C

1 reference

GOA release 2020-03-11

membrane protein

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based on heuristic

inferred from title

Mark Hochstrasser

5

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author name string

Gregory Huyer

1

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Wachirapon F Piluek

2

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Zoya Fansler

3

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Stefan G Kreft

4

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Jeffrey L Brodsky

6

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Susan Michaelis

7

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language of work or name

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publication date

10 September 2004

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Journal of Biological Chemistry

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1 December 2016

279

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37

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38369-78

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Rapid degradation of a large fraction of newly synthesized proteins by proteasomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Conformational disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Traffic jam: a compendium of human diseases that affect intracellular transport processes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Traffic jams II: an update of diseases of intracellular transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Folding proteins in fatal ways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Secretory pathway quality control operating in Golgi, plasmalemmal, and endosomal systems

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Protein degradation and protection against misfolded or damaged proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

ER-associated degradation in protein quality control and cellular regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Degradation of CFTR by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

ER-golgi traffic is a prerequisite for efficient ER degradation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

A striking quality control subcompartment in Saccharomyces cerevisiae: the endoplasmic reticulum-associated compartment

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The a-factor pheromone of Saccharomyces cerevisiae is essential for mating

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Studies on transformation of Escherichia coli with plasmids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Targeting of E. coli β-galactosidase to the nucleus in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Expression of hepatitis B virus surface antigen in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The action of molecular chaperones in the early secretory pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The engagement of Sec61p in the ER dislocation process

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Receptor downregulation and multivesicular-body sorting

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

When ubiquitin meets ubiquitin receptors: a signalling connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

The ER translocon and retrotranslocation: is the shift into reverse manual or automatic?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

A membrane protein required for dislocation of misfolded proteins from the ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Membrane-bound transcription factors: regulated release by RIP or RUP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

Endoproteolytic activity of the proteasome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402468200

21 January 2018

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