(Q28069232)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

review article

1 reference

title

Cancer Stem Cells and Radioresistance: Rho/ROCK Pathway Plea Attention (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

neoplastic stem cells

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Annapurna Pranatharthi

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Cecil Ross

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

language of work or name

1 reference

15 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

language of work

Stem Cells International

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

volume

2016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

page(s)

5785786

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

22 March 2020

copyright license

start time

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

20 March 2017

1 reference

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

20 March 2017

1 reference

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Interaction between ROCK II and nucleophosmin/B23 in the regulation of centrosome duplication

20 March 2017

1 reference

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Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase

20 March 2017

1 reference

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Prospective identification of tumorigenic breast cancer cells

20 March 2017

1 reference

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Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

20 March 2017

1 reference

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Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

20 March 2017

1 reference

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

20 March 2017

1 reference

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Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP

20 March 2017

1 reference

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Genomic analysis of metastasis reveals an essential role for RhoC

20 March 2017

1 reference

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Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity

20 March 2017

1 reference

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Prostate cancer stem cells: a new target for therapy

20 March 2017

1 reference

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CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Identification of pancreatic cancer stem cells

20 March 2017

1 reference

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Rho GTPases and signaling networks

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Rho GTPases and their effector proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Association of reactive oxygen species levels and radioresistance in cancer stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

High RhoA expression at the tumor front in clinically localized prostate cancer and association with poor tumor differentiation.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Activated Thyroid Hormone Promotes Differentiation and Chemotherapeutic Sensitization of Colorectal Cancer Stem Cells by Regulating Wnt and BMP4 Signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoA is associated with invasion and poor prognosis in colorectal cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoC is essential in TGF-β1 induced epithelial-mesenchymal transition in cervical cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoC and ROCKs regulate cancer cell interactions with endothelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

HMG-CoA reductase inhibitors as adjuvant treatment for hematologic malignancies: what is the current evidence?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Simvastatin Enhances the Effects of Radiotherapy and Cetuximab on a Cell Line (FaDu) Derived from a Squamous Cell Carcinoma of Head and Neck

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

CDC42 inhibition suppresses progression of incipient intestinal tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

The role of RhoC in epithelial-to-mesenchymal transition of ovarian carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoC regulates cancer stem cells in head and neck squamous cell carcinoma by overexpressing IL-6 and phosphorylation of STAT3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Reduced esophageal cancer incidence in statin users, particularly with cyclo-oxygenase inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Notching up MYC gives a LIC.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RHPN2 drives mesenchymal transformation in malignant glioma by triggering RhoA activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Overexpression of Ras homologous C (RhoC) induces malignant transformation of hepatocytes in vitro and in nude mouse xenografts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

TGF-β mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Acute and fractionated irradiation differentially modulate glioma stem cell division kinetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

MYC regulation of CHK1 and CHK2 promotes radioresistance in a stem cell-like population of nasopharyngeal carcinoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoC impacts the metastatic potential and abundance of breast cancer stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

The small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Potential use of HMG-CoA reductase inhibitors (statins) as radioprotective agents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Hypoxia inducible factors in cancer stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

ABCG2: the key to chemoresistance in cancer stem cells?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Rho GTPases in cancer cell biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

The Survivin-mediated radioresistant phenotype of glioblastomas is regulated by RhoA and inhibited by the green tea polyphenol (-)-epigallocatechin-3-gallate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

RhoB in cancer suppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Cancer stem cells in nervous system tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Effect of RhoA gene silencing on proliferation and migration of gastric MGC-803 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

The Rho exchange factor Net1 is regulated by nuclear sequestration

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5002480

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

2 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

Spinal RhoA/Rho kinase signalling pathway may participate in the development of bone cancer pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

RhoC upregulation is correlated with reduced E-cadherin in human breast cancer specimens after chemotherapy and in human breast cancer MCF-7 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

Molecular switches in metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

Deoxyribose Nucleic Acid Values in Tumour Cells with Reference to the Stem-cell Theory of Tumour Growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

Stem Cells and Cancer: Two Faces of Eve

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F5785786

BRCA2 and Nucleophosmin Coregulate Centrosome Amplification and Form a Complex with the Rho Effector Kinase ROCK2

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27597870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Significant association of Rho/ROCK pathway with invasion and metastasis of bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27597870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Abstracts of the ACUTE LEUKEMIAS XV : Biology and Treatment Strategies, February 22- 25, 2015, Munich, Germany

1 reference

https://pubmed.ncbi.nlm.nih.gov/27597870

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2016/5785786

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27597870%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

27597870

2 references