Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28083481)
Watch
English
What can triumphs and tribulations from drug research in Alzheimer's disease tell us about the development of psychotropic drugs in general?
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
review article
1 reference
stated in
Europe PubMed Central
title
What can triumphs and tribulations from drug research in Alzheimer's disease tell us about the development of psychotropic drugs in general?
(English)
1 reference
stated in
PubMed
main subject
Alzheimer's disease
1 reference
based on heuristic
inferred from title
author name string
Robert E Becker
series ordinal
1
1 reference
stated in
Crossref
Mary V Seeman
series ordinal
2
1 reference
stated in
Crossref
Nigel H Greig
series ordinal
3
1 reference
stated in
Crossref
Debomoy K Lahiri
series ordinal
4
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
August 2015
1 reference
stated in
PubMed
published in
The Lancet Psychiatry
1 reference
stated in
PubMed
volume
2
1 reference
stated in
PubMed
issue
8
1 reference
stated in
PubMed
page(s)
756-64
1 reference
stated in
PubMed
cites work
Biological insights from 108 schizophrenia-associated genetic loci
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
20 March 2017
Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
20 March 2017
Believe it or not: how much can we rely on published data on potential drug targets?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
7 April 2017
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
7 April 2017
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
7 April 2017
Animal models of neuropsychiatric disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
7 April 2017
Retrieval induces adaptive forgetting of competing memories via cortical pattern suppression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Placebo response in antipsychotic clinical trials: a meta-analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Antidepressant drug development: Focus on triple monoamine reuptake inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Biomarkers and clinical staging in psychiatry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
A new regulatory road-map for Alzheimer's disease drug development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
A new, evidence-based estimate of patient harms associated with hospital care
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Psychiatric drug development: diagnosing a crisis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Neurodevelopmental model of schizophrenia: update 2012
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
β-Amyloid burden in healthy aging: regional distribution and cognitive consequences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Resolving controversies on the path to Alzheimer's therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Neuropsychiatric symptoms in Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Prevention of the first episode of psychosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Lost in translation: neuropsychiatric drug development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Psychiatrists' relationships with industry: the principal-agent problem
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Why so few drugs for Alzheimer's disease? Are methods failing drugs?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The structure and function of Alzheimer's gamma secretase enzyme complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Fifty years chlorpromazine: a historical perspective
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
What CATIE found: results from the schizophrenia trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The history of clozapine and its emergence in the US market: a review and analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
The history and contemporary challenges of the US Food and Drug Administration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Experimental animal models for the simulation of depression and anxiety.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Why olanzapine beats risperidone, risperidone beats quetiapine, and quetiapine beats olanzapine: an exploratory analysis of head-to-head comparison studies of second-generation antipsychotics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
EFFECT OF CHLORPROMAZINE OR HALOPERIDOL ON FORMATION OF 3METHOXYTYRAMINE AND NORMETANEPHRINE IN MOUSE BRAIN.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Atypical antipsychotics: mechanism of action.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Treatment of the schizophrenia prodrome: is it presently ethical?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Clozapine-induced agranulocytosis. Incidence and risk factors in the United States
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
29 September 2017
Multimodal prediction of dementia with up to 10 years follow up: the Gothenburg MCI study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
2 June 2018
Frequency of stages of Alzheimer-related lesions in different age categories
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
2 June 2018
The history of clozapine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
2 June 2018
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
2 June 2018
Mining the genomes of exceptional responders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Remembering Sir William Osler 100 years after his death: what can we learn from his legacy?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Industry withdrawal from psychiatric medication development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Tracking the earliest pathologic changes in Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
A new roadmap for drug development for Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Moving towards early clinical trials for amyloid-targeted therapy in Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Psychiatry beyond the current paradigm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Rebalancing academic psychiatry: why it needs to happen - and soon.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Epigenetics: a paradigm shift in understanding Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Alois Alzheimer (1864-1915) and the Alzheimer syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Is pharma running out of brainy ideas?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Tarenflurbil for Alzheimer's disease: a "shot on goal" that missed
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Can phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5161453
retrieved
27 November 2018
Atypical Antipsychotics: Mechanism of Action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS2215-0366%2815%2900214-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S2215-0366(15)00214-X
1 reference
stated in
PubMed
PMC publication ID
5161453
1 reference
stated in
PubMed
PubMed publication ID
26249306
1 reference
stated in
PubMed
ResearchGate publication ID
280575379
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
