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Prioritizing therapeutic targets using patient-derived xenograft models
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scholarly article
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PubMed
review article
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Europe PubMed Central
title
Prioritizing therapeutic targets using patient-derived xenograft models
(English)
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stated in
PubMed
main subject
patient
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based on heuristic
inferred from title
xenograft
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based on heuristic
inferred from title
prioritization
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based on heuristic
inferred from title
author name string
K.A. Lodhia
series ordinal
1
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Crossref
A.M. Hadley
series ordinal
2
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Crossref
P. Haluska
series ordinal
3
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Crossref
C.L. Scott
series ordinal
4
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
April 2015
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PubMed
published in
Biochimica et Biophysica Acta
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PubMed
volume
1855
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PubMed
page(s)
223-34
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PubMed
issue
2
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
A clinically relevant, syngeneic model of spontaneous, highly metastatic B16 mouse melanoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Preclinical development of molecular-targeted agents for cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Optimizing outcomes for patients with advanced disease in chronic myelogenous leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
The role of the p53 pathway in the treatment of follicular lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Methods in cell separations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
The resurgence of platinum-based cancer chemotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
A new model of patient tumor-derived breast cancer xenografts for preclinical assays
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Establishment of human tumor xenografts in immunodeficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Progression of renal cell carcinoma is inhibited by genistein and radiation in an orthotopic model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Beyond mere markers: functions for CD34 family of sialomucins in hematopoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Identification and isolation of hematopoietic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Human tumor xenografts as predictive preclinical models for anticancer drug activity in humans: better than commonly perceived-but they can be improved
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Injection of human primary effusion lymphoma cells or associated macrophages into severe combined immunodeficient mice causes murine lymphomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
An orthotopic model for human uveal melanoma in SCID mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
Growth characteristics and metastatic properties of human breast cancer xenografts in immunodeficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
The SCID mouse mutant: definition, characterization, and potential uses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
29 September 2017
The SCID/Beige mouse as a model to investigate protection against Yersinia pestis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
2 June 2018
Comparative properties of five human ovarian adenocarcinoma cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
2 June 2018
Melanoma: smart therapeutic strategies in immuno-oncology.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Amplification but not translocation of anaplastic lymphoma kinase is a frequent event in oesophageal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
A missing link in genotype-directed cancer therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Characterization of a large panel of patient-derived tumor xenografts representing the clinical heterogeneity of human colorectal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Characterization of Lymphomas Developing in Immunodeficient Mice Implanted With Primary Human Non–Small Cell Lung Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Rare cancers are not so rare: the rare cancer burden in Europe.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Patient-derived first generation xenografts of non-small cell lung cancers: promising tools for predicting drug responses for personalized chemotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Combination therapy of an orthotopic renal cell carcinoma model using intratumoral vector-mediated costimulation and systemic interleukin-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Personal mouse colonies give hope for pancreatic cancer patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
Development of a chemoresistant orthotopic human nonsmall cell lung carcinoma model in nude mice: analyses of tumor heterogenity in relation to the immunohistochemical levels of expression of cyclooxygenase-2, ornithine decarboxylase, lung-related r
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433556
retrieved
27 November 2018
An in vivo platform for translational drug development in pancreatic cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tumor growth inhibition by olaparib in BRCA2 germline-mutated patient-derived ovarian cancer tissue xenografts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
SCID-bg mice as xenograft recipients
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Efficient engraftment of human primary breast cancer transplants in nonconditioned NOD/Scid mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Multigene panel testing: planning the next generation of research studies in clinical cancer genetics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of human pancreatic orthotopic tumor xenografts suitable for drug screening
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Preclinical drug development: rationale and methods
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25783201
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBCAN.2015.03.002
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2981546
Fatcat ID
release_s3ejzb44lfcvlj7so4tmvooidi
0 references
OpenCitations bibliographic resource ID
2981546
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2981546
PMCID
4433556
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2981546
PubMed ID
25783201
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2981546
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