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Innate immune interactions within the central nervous system modulate pathogenesis of viral infections
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title
Innate immune interactions within the central nervous system modulate pathogenesis of viral infections
(English)
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PubMed
main subject
pathogenesis
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author
Michael S. Diamond
series ordinal
2
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author name string
Sharmila Nair
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1
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language of work or name
English
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publication date
October 2015
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published in
Current Opinion in Immunology
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PubMed
volume
36
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PubMed
page(s)
47-53
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PubMed
cites work
IL-1β signaling promotes CNS-intrinsic immune control of West Nile virus infection
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Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection
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Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing
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Alteration of blood-brain barrier integrity by retroviral infection
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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection
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20 March 2017
Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis
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Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection
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20 March 2017
Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1
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20 March 2017
Axonal transport mediates West Nile virus entry into the central nervous system and induces acute flaccid paralysis
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Cell-Specific IRF-3 Responses Protect against West Nile Virus Infection by Interferon-Dependent and -Independent Mechanisms
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20 March 2017
PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons
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Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein
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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
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Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis
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20 March 2017
The interferon-inducible gene viperin restricts West Nile virus pathogenesis
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Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
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7 April 2017
Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier
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IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis
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29 September 2017
Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals
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29 September 2017
Type I interferon protects mice from fatal neurotropic infection with Langat virus by systemic and local antiviral responses.
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29 September 2017
Intrinsic innate immunity fails to control herpes simplex virus and vesicular stomatitis virus replication in sensory neurons and fibroblasts
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29 September 2017
A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency
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29 September 2017
Interferon regulatory factor-1 protects from fatal neurotropic infection with vesicular stomatitis virus by specific inhibition of viral replication in neurons
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29 September 2017
Interferon-stimulated genes: a complex web of host defenses
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29 September 2017
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5.
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29 September 2017
MicroRNA-29b modulates Japanese encephalitis virus-induced microglia activation by targeting tumor necrosis factor alpha-induced protein 3.
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29 September 2017
Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects
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29 September 2017
Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging
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29 September 2017
A role for Ifit2 in restricting West Nile virus infection in the brain
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29 September 2017
Antiviral type I and type III interferon responses in the central nervous system
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29 September 2017
Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death
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29 September 2017
IL-1R1 is required for dendritic cell-mediated T cell reactivation within the CNS during West Nile virus encephalitis
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29 September 2017
Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses
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29 September 2017
MicroRNAs in the brain: it's regulatory role in neuroinflammation
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29 September 2017
An attenuating mutation in a neurovirulent Sindbis virus strain interacts with the IPS-1 signaling pathway in vivo
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29 September 2017
A neuron-specific role for autophagy in antiviral defense against herpes simplex virus
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29 September 2017
Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood
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29 September 2017
Herpesvirus transport to the nervous system and back again.
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29 September 2017
West Nile virus infection causes endocytosis of a specific subset of tight junction membrane proteins
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29 September 2017
Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis
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29 September 2017
Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery
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29 September 2017
TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice
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29 September 2017
NLRP3 inflammasome: key mediator of neuroinflammation in murine Japanese encephalitis
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29 September 2017
RIG-I mediates innate immune response in mouse neurons following Japanese encephalitis virus infection
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29 September 2017
Rabies virus as a transneuronal tracer of neuronal connections
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29 September 2017
Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis
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29 September 2017
Rabies virus infection induces type I interferon production in an IPS-1 dependent manner while dendritic cell activation relies on IFNAR signaling
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29 September 2017
Interferon regulatory factor 3-dependent pathways are critical for control of herpes simplex virus type 1 central nervous system infection
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29 September 2017
Autophagy protects against Sindbis virus infection of the central nervous system
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29 September 2017
Reversal of West Nile virus-induced blood-brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor
1 reference
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PubMed Central
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29 September 2017
HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein
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PubMed Central
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29 September 2017
Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans
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29 September 2017
TLR3 deficiency in patients with herpes simplex encephalitis
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PubMed Central
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29 September 2017
MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus
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PubMed Central
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29 September 2017
Canine distemper virus uses both the anterograde and the hematogenous pathway for neuroinvasion
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29 September 2017
Neurons produce type I interferon during viral encephalitis
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PubMed Central
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29 September 2017
Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus
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29 September 2017
Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway
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29 September 2017
Virus receptors in the human central nervous system
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29 September 2017
Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis
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PubMed Central
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2 June 2018
The TLR3/TICAM-1 pathway is mandatory for innate immune responses to poliovirus infection
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2 June 2018
Local type I IFN receptor signaling protects against virus spread within the central nervous system
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4593735
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27 November 2018
Mechanism of neuroinvasion of Venezuelan equine encephalitis virus in the mouse
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27 November 2018
Identifiers
DOI
10.1016/J.COI.2015.06.011
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PMC publication ID
4593735
1 reference
stated in
PubMed
PubMed publication ID
26163762
1 reference
stated in
PubMed
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