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An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation
scientific journal article
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scholarly article
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
title
An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation
(English)
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
main subject
Mcm10p YIL150C
1 reference
stated in
GOA release 2020-03-11
author
Daniel L. Kaplan
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
author name string
Patricia Perez-Arnaiz
series ordinal
1
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
language of work or name
English
0 references
publication date
15 October 2016
1 reference
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
published in
Journal of Molecular Biology
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
volume
428
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
issue
23
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
page(s)
4608-4625
1 reference
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
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The replication initiation protein Sld2 regulates helicase assembly
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Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation
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Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress
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GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks
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Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex
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Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase
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29 September 2017
Mcm10 coordinates the timely assembly and activation of the replication fork helicase
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29 September 2017
Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase
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29 September 2017
A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA
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29 September 2017
Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression
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29 September 2017
MCM10: one tool for all-Integrity, maintenance and damage control.
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29 September 2017
ATPase-dependent quality control of DNA replication origin licensing
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29 September 2017
Enigmatic roles of Mcm10 in DNA replication
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29 September 2017
Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components
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29 September 2017
Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase.
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29 September 2017
Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA.
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29 September 2017
Cyclin-dependent kinase-dependent initiation of chromosomal DNA replication
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29 September 2017
The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.
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29 September 2017
The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
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29 September 2017
Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins
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29 September 2017
Incorporation into the prereplicative complex activates the Mcm2-7 helicase for Cdc7-Dbf4 phosphorylation
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29 September 2017
Cell cycle regulation of DNA replication.
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29 September 2017
Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin
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29 September 2017
Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression
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PubMed Central
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29 September 2017
Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding
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PubMed Central
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29 September 2017
The Cdc23 (Mcm10) protein is required for the phosphorylation of minichromosome maintenance complex by the Dfp1-Hsk1 kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
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29 September 2017
Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45.
1 reference
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PubMed Central
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29 September 2017
Mutants of S. cerevisiae defective in the maintenance of minichromosomes.
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PubMed Central
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29 September 2017
Regulated eukaryotic DNA replication origin firing with purified proteins
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PubMed Central
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2 June 2018
Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
2 June 2018
GINS and Sld3 compete with one another for Mcm2-7 and Cdc45 binding
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
2 June 2018
The physical interaction of Mcm10 with Cdc45 modulates their DNA-binding properties
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
27 November 2018
Mcm10 plays a role in functioning of the eukaryotic replicative DNA helicase, Cdc45-Mcm-GINS.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
27 November 2018
Origin association of Sld3, Sld7, and Cdc45 proteins is a key step for determination of origin-firing timing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
27 November 2018
Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
27 November 2018
Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
retrieved
27 November 2018
Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
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27 November 2018
Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5115986
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27 November 2018
New temperature-sensitive mutants of Saccharomyces cerevisiae affecting DNA replication
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27751725
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JMB.2016.10.014
1 reference
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
PMCID
5115986
1 reference
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
PubMed ID
27751725
2 references
stated in
PubMed
PubMed ID
27751725
retrieved
3 January 2017
stated in
Europe PubMed Central
PMCID
5115986
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27751725%20AND%20SRC:MED&resulttype=core&format=json
retrieved
25 March 2020
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