(Q28114848)

3 January 2017

title

Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros gene (English)

1 reference

IKAROS family zinc finger 1

3 January 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

1 reference

Frederick D. Goldman

1

1 reference

3 January 2017

Zafer Gurel

2

1 reference

3 January 2017

Duha Al-Zubeidi

3

1 reference

3 January 2017

Ari J. Fried

4

1 reference

3 January 2017

Michael Icardi

5

1 reference

3 January 2017

Chunhua Song

6

1 reference

3 January 2017

Sinisa Dovat

7

1 reference

3 January 2017

publication date

1 April 2012

1 reference

3 January 2017

published in

Pediatric Blood Cancer

1 reference

3 January 2017

volume

58

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3 January 2017

issue

4

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3 January 2017

page(s)

591–597

1 reference

describes a project that uses

3 January 2017

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3161153/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The role of Ikaros in human erythroid differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Ikaros interactions with CtBP reveal a repression mechanism that is independent of histone deacetylase activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Ikaros regulates neutrophil differentiation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

The Ikaros gene is required for the development of all lymphoid lineages

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Ikaros stability and pericentromeric localization are regulated by protein phosphatase 1.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Recruitment of ikaros to pericentromeric heterochromatin is regulated by phosphorylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Fibroblast growth factor receptor 4 is a target for the zinc-finger transcription factor Ikaros in the pituitary

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

High frequency of Ikaros isoform 6 expression in acute myelomonocytic and monocytic leukemias: implications for up-regulation of the antiapoptotic protein Bcl-XL in leukemogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Defects in hemopoietic stem cell activity in Ikaros mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

2 June 2018

1 reference

Ikaros is critical for B cell differentiation and function.

21 January 2018

1 reference

Ikaros increases normal apoptosis in adult erythroid cells

21 January 2018

1 reference

Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.

21 January 2018

1 reference

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

21 January 2018

1 reference

Submicroscopic deletions in 5q- associated malignancies

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161153

Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia

27 November 2018

1 reference

12 December 2020

Binding of Ikaros to the lambda5 promoter silences transcription through a mechanism that does not require heterochromatin formation

1 reference

12 December 2020

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

12 December 2020

Ikaros sets thresholds for T cell activation and regulates chromosome propagation

1 reference

12 December 2020

Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1002/PBC.23160

1 reference

1 reference

1 reference

1 reference