(Q28114960)

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Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition

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scholarly article

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3 January 2017

Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition (English)

1 reference

3 January 2017

Aldehyde dehydrogenase 18 family, member A1

1 reference

GOA release 2020-03-11

author name string

C. A. Hu

1

1 reference

3 January 2017

W. W. Lin

2

1 reference

3 January 2017

C. Obie

3

1 reference

3 January 2017

D. Valle

4

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3 January 2017

language of work or name

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publication date

5 March 1999

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3 January 2017

Journal of Biological Chemistry

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3 January 2017

274

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3 January 2017

6754–6762

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3 January 2017

10

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3 January 2017

A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.

1 reference

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21 January 2018

Pyrroline-5-carboxylate synthase activity in mammalian cells

1 reference

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21 January 2018

A bifunctional enzyme (delta 1-pyrroline-5-carboxylate synthetase) catalyzes the first two steps in proline biosynthesis in plants

1 reference

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"On" and "Off" Responses of K+-Induced Synaptosomal Proline Release: Involvement of the Sodium Pump

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NMDA receptor-mediated depolarizing action of proline on CA1 pyramidal cells

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Molecular cloning and expression of a high affinity L-proline transporter expressed in putative glutamatergic pathways of rat brain

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Correlation between the induction of a gene for delta 1-pyrroline-5-carboxylate synthetase and the accumulation of proline in Arabidopsis thaliana under osmotic stress.

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Isolation, characterization, and chromosomal location of a gene encoding the delta 1-pyrroline-5-carboxylate synthetase in Arabidopsis thaliana

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Cloning of a polycistronic cDNA from tomato encoding gamma-glutamyl kinase and gamma-glutamyl phosphate reductase

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Analysis of theEscherichia coli proBAlocus by DNA and protein sequencing

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Proline biosynthesis: multiple defects in Chinese hamster ovary cells.

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The importance of ornithine as a precursor for proline in mammalian cells

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Chromosomal localization of human aspartate aminotransferase genes by in situ hybridization

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Statistical features of human exons and their flanking regions

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Basic local alignment search tool

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Cloning, characterization, and expression of cDNAs encoding human delta 1-pyrroline-5-carboxylate dehydrogenase

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21 January 2018

At least two mutant alleles of ornithine delta-aminotransferase cause gyrate atrophy of the choroid and retina in Finns.

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Regulatable promoters of Saccharomyces cerevisiae: comparison of transcriptional activity and their use for heterologous expression

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A simple and efficient method for direct gene deletion in Saccharomyces cerevisiae

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Gene-enzyme relationships in the proline biosynthetic pathway of Saccharomyces cerevisiae

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Electroporation efficiency in mammalian cells is increased by dimethyl sulfoxide (DMSO).

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Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif

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The Blocks database--a system for protein classification

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Removal of feedback inhibition of delta 1-pyrroline-5-carboxylate synthetase, a bifunctional enzyme catalyzing the first two steps of proline biosynthesis in plants.

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Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

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Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae

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Factors influencing pyrroline 5-carboxylate synthesis from glutamate by rat intestinal mucosa mitochondria

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Analysis of the Serratia marcescens proBA operon and feedback control of proline biosynthesis

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Role of serine 352 in the allosteric response of Serratia marcescens aspartokinase I-homoserine dehydrogenase I analyzed by using site-directed mutagenesis

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Escherichia coli UMP-kinase, a member of the aspartokinase family, is a hexamer regulated by guanine nucleotides and UTP

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Multicopy suppressors, mssA and mssB, of an smbA mutation of Escherichia coli.

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Splice Junctions: Association with Variation in Protein Structure

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RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

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Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing

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The regulation of splice-site selection, and its role in human disease

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A coactivator of pre-mRNA splicing

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21 January 2018

Directing alternative splicing: cast and scenarios

1 reference

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Common themes in the function of transcription and splicing enhancers

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SR proteins and splicing control

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Cytochrome c: can't live with it--can't live without it.

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Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing.

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Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila

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Exon-intron boundary sliding in the generation of two mRNAs coding for porcine urokinase-like plasminogen activator.

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Organization of the human beta-adducin gene (ADD2)

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Expression and alternative processing of a chicken gene encoding both growth hormone-releasing hormone and pituitary adenylate cyclase-activating polypeptide.

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Analysis of the 5' sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease

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Arginine-metabolizing enzymes in the developing rat small intestine

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Development of ornithine metabolism in the mouse intestine

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Synthesis of citrulline from glutamine in pig enterocytes

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Proline inhibition of pyrroline-5-carboxylate reductase: Differences in enzymes obtained from animal and tissue culture sources

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Decreased cysteine and proline synthesis in parenterally fed, premature infants

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Compartmentation of endogenously synthesized amino acids in neonates

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Enzymological evidence for the indispensability of small intestine in the synthesis of arginine from glutamate. I. Pyrroline-5-carboxylate synthase

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Toxicity of L-proline toward rat hippocampal neurons

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Mammalian Brain-specific L-Proline Transporter

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Synteny between the Pro+ marker and human glutamate oxaloacetate transaminase

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Influence of deoxyspergualin on mononuclear phagocytic system in mice

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Domain structure of mitochondrial and chloroplast targeting peptides

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Regulation of proline biosynthesis: The inhibition of pyrroline-5-carboxylate synthase activity by ornithine

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Intestinal metabolism of glutamine and glutamate from the lumen as compared to glutamine from blood

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Ytterbium acetate as a particulate-phase digesta-flow marker

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Changes in ornithine metabolic enzymes induced by dietary protein in small intestine and liver: intestine-liver relationship in ornithine supply to liver

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Mice lacking ornithine-delta-aminotransferase have paradoxical neonatal hypoornithinaemia and retinal degeneration

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Identifiers

10.1074/JBC.274.10.6754

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1 reference

3 January 2017

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