(Q28118752)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Fine specificity and molecular competition in SLAM family receptor signalling (English)

2 references

4 January 2017

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11 March 2020

1

1 reference

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11 March 2020

Clive M. Metcalfe

3

1 reference

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11 March 2020

author name string

Elliott King

4

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Stefanie Margraf

5

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

Lee I Garner

2

1 reference

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11 March 2020

Marion H Brown

6

1 reference

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11 March 2020

language of work or name

English

0 references

publication date

18 March 2014

1 reference

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11 March 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

volume

9

2 references

4 January 2017

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11 March 2020

page(s)

e92184

2 references

4 January 2017

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11 March 2020

issue

3

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

11 March 2020

copyright license

start time

18 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

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Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP

20 March 2017

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Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

20 March 2017

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Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP

20 March 2017

1 reference

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SAP couples Fyn to SLAM immune receptors

20 March 2017

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Identification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adapters

20 March 2017

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Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells

20 March 2017

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CD6 regulates T-cell responses through activation-dependent recruitment of the positive regulator SLP-76

20 March 2017

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NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease

20 March 2017

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Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

20 March 2017

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Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function

20 March 2017

1 reference

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Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors

20 March 2017

1 reference

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Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family

20 March 2017

1 reference

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CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A

20 March 2017

1 reference

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Defective NK cell activation in X-linked lymphoproliferative disease

20 March 2017

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Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The SIRP family of receptors and immune regulation

20 March 2017

1 reference

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EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene

20 March 2017

1 reference

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An investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-b

20 March 2017

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Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells

20 March 2017

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Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

20 March 2017

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Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor

20 March 2017

1 reference

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The International Protein Index: an integrated database for proteomics experiments

20 March 2017

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Systems model of T cell receptor proximal signaling reveals emergent ultrasensitivity

7 April 2017

1 reference

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Non-catalytic tyrosine-phosphorylated receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The receptor Ly108 functions as a SAP adaptor-dependent on-off switch for T cell help to B cells and NKT cell development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Positive and negative signaling through SLAM receptors regulate synapse organization and thresholds of cytolysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Labile disulfide bonds are common at the leucocyte cell surface.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

SLAM family receptors and SAP adaptors in immunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Biochemical and genetic evidence for a SAP-PKC-theta interaction contributing to IL-4 regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The XLP syndrome protein SAP interacts with SH3 proteins to regulate T cell signaling and proliferation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The SLAM and SAP gene families control innate and adaptive immune responses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

The isoforms of phospholipase C-gamma are differentially used by distinct human NK activating receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

NTB-A, a new activating receptor in T cells that regulates autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

SAP mediates specific cytotoxic T-cell functions in X-linked lymphoproliferative disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

2B4 is constitutively associated with linker for the activation of T cells in glycolipid-enriched microdomains: properties required for 2B4 lytic function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Essential role of the tyrosine kinase substrate phospholipase C-gamma1 in mammalian growth and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Defective natural killing activity but retention of lymphocyte-mediated antibody-dependent cellular cytotoxicity in patients with the X-linked lymphoproliferative syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Production of human cells expressing individual transferred HLA-A,-B,-C genes using an HLA-A,-B,-C null human cell line

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3958483

Cell-mediated immunity to Epstein-Barr virus (EBV) and natural killer (NK)-cell activity in the X-linked lymphoproliferative syndrome

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0092184

Cutting Edge: Defective NK Cell Activation in X-Linked Lymphoproliferative Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0092184

SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0092184

CPFP: a central proteomics facilities pipeline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0092184

Phospholipase C-gamma 2 is a critical signaling mediator for murine NK cell activating receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0092184

Tandem SH2 domains confer high specificity in tyrosine kinase signaling

21 January 2018

1 reference

12 December 2020

The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells

1 reference

12 December 2020

Differential and nonredundant roles of phospholipase Cgamma2 and phospholipase Cgamma1 in the terminal maturation of NK cells

1 reference

12 December 2020

Direct and indirect interactions of the cytoplasmic region of CD244 (2B4) in mice and humans with FYN kinase

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0092184

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

2 references

4 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24642916%20AND%20SRC:MED&resulttype=core&format=json