Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28138479)
Watch
English
The G2-phase DNA-damage checkpoint
scientific article (publication date: July 2000)
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
The G2-phase DNA-damage checkpoint
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
main subject
DNA damage
0 references
author
Tony Carr
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
author name string
M J O'Connell
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
N C Walworth
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
language of work or name
English
0 references
publication date
1 July 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
published in
Trends in Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
volume
10
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
page(s)
296-303
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
cites work
Universal control mechanism regulating onset of M-phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-dependent protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of cell cycle arrest by the Mec1sc/Rad3sp DNA structure checkpoint pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Rad3–Rad26 complex responds to DNA damage independently of other checkpoint proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A sliding clamp model for the Rad1 family of cell cycle checkpoint proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel Rad24 checkpoint protein complex closely related to replication factor C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast checkpoint genes in DNA damage processing: implications for repair and arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9–Rad9 interaction after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc2 Phosphorylation of Crb2 Is Required for Reestablishing Cell Cycle Progression after the Damage Checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Xenopus Chk1 protein kinase mediates a caffeine-sensitive pathway of checkpoint control in cell-free extracts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication checkpoint enforced by kinases Cds1 and Chk1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of 14-3-3 proteins and nuclear export control the intracellular localization of the mitotic inducer Cdc25.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Feedback controls and G2 checkpoints: fission yeast as a model system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of inhibitory CDC2 phosphorylation in radiation-induced G2 arrest in human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear localization of cyclin B1 controls mitotic entry after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear export of cyclin B1 and its possible role in the DNA damage-induced G2 checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling of mitosis to the completion of S phase through Cdc34-mediated degradation of Wee1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Meiotic DNA replication checkpoint control in fission yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Entry into mitosis in vertebrate somatic cells is guarded by a chromosome damage checkpoint that reverses the cell cycle when triggered during early but not late prophase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2800%2901773-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0962-8924(00)01773-6
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed ID
10856933
1 reference
stated in
Europe PubMed Central
PubMed ID
10856933
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10856933%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
ResearchGate publication ID
12461595
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit