(Q28139721)

English

The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation

scientific article (publication date: 2 April 1999)

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scholarly article

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The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation (English)

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author name string

S O Meakin

1

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J I MacDonald

2

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E A Gryz

3

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C J Kubu

4

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J M Verdi

5

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language of work or name

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publication date

2 April 1999

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Journal of Biological Chemistry

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274

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9861-70

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14

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Functions of the neurotrophins during nervous system development: what the knockouts are teaching us.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Role of the neurotrophic factors BDNF and NGF in the commitment of pluripotent neural crest cells

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21 January 2018

A reciprocal cell-cell interaction mediated by NT-3 and neuregulins controls the early survival and development of sympathetic neuroblasts

1 reference

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21 January 2018

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Cellular targets and trophic functions of neurotrophin-3 in the developing rat hippocampus

1 reference

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21 January 2018

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Grasping objects: the cortical mechanisms of visuomotor transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Signal transduction by the neurotrophin receptors

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https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

The nerve growth factor family of receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

SNT, a differentiation-specific target of neurotrophic factor-induced tyrosine kinase activity in neurons and PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

A family of proteins that inhibit signalling through tyrosine kinase receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

A novel genetic system to detect protein-protein interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of src and ras actions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin-like growth factor I receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.14.9861

21 January 2018

Identifiers

10.1074/JBC.274.14.9861

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