(Q28140238)

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

scientific article (publication date: April 2000)

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets (English)

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R A Clynes

1

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T L Towers

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L G Presta

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J V Ravetch

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4

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English

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publication date

April 2000

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Nature Medicine

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volume

6

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443-6

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4

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cites work

Fc receptors are required in passive and active immunity to melanoma

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p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

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Growth inhibition of CD20-positive B lymphoma cell lines by IDEC-C2B8 anti-CD20 monoclonal antibody

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Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment

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Humanization of an anti-p185HER2 antibody for human cancer therapy

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FcR gamma chain deletion results in pleiotrophic effector cell defects

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Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

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21 January 2018

Characterization of complex formation by humanized anti-IgE monoclonal antibody and monoclonal human IgE.

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21 January 2018

Inhibitory pathways triggered by ITIM-containing receptors.

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Use of rituximab, the new FDA-approved antibody.

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Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

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Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas

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(Q28140238)

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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