(Q28141120)

English

Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization

scientific article (publication date: 22 September 2000)

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scholarly article

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Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization (English)

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author name string

H Togashi

1

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K Nagata

2

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M Takagishi

3

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N Saitoh

4

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M Inagaki

5

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language of work or name

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publication date

22 September 2000

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Journal of Biological Chemistry

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275

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38

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29570-8

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The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.

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Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

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Deletion analysis of the lambda tR1 termination region. Effect of sequences near the transcript release sites, and the minimum length of rho-dependent transcripts

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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

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Myosin II activation promotes neurite retraction during the action of Rho and Rho-kinase.

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Balance between activities of Rho kinase and type 1 protein phosphatase modulates turnover of phosphorylation and dynamics of desmin/vimentin filaments

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The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

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Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells

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Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member

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10.1074/JBC.M003726200

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