(Q28141139)

English

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

scientific article (publication date: 14 April 2000)

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scholarly article

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Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL (English)

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author name string

D Sakkab

1

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M Lewitzky

2

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G Posern

3

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U Schaeper

4

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M Sachs

5

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W Birchmeier

6

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S M Feller

7

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language of work or name

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publication date

14 April 2000

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Journal of Biological Chemistry

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275

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15

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10772-8

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Protein modules and signalling networks

1 reference

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Physiological signals and oncogenesis mediated through Crk family adapter proteins

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A novel viral oncogene with structural similarity to phospholipase C

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Role of Crk oncogene product in physiologic signaling.

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

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The myotonic dystrophy kinase-related Cdc42-binding kinase is involved in the regulation of neurite outgrowth in PC12 cells

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Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

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C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180

1 reference

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Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

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21 January 2018

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

1 reference

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21 January 2018

Activation of Rac1 by a Crk SH3-binding protein, DOCK180

1 reference

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21 January 2018

Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

1 reference

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The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins

1 reference

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21 January 2018

Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

1 reference

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21 January 2018

SH2 domains recognize specific phosphopeptide sequences

1 reference

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21 January 2018

Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

1 reference

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21 January 2018

Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes

1 reference

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Activity of Rap1 is regulated by bombesin, cell adhesion, and cell density in NIH3T3 fibroblasts

1 reference

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Mitogenic and oncogenic properties of the small G protein Rap1b

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In search of a function for the Ras-like GTPase Rap1.

1 reference

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Rapid Ca2+-mediated activation of Rap1 in human platelets

1 reference

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21 January 2018

Hepatocyte growth factor: a multifunctional cytokine

1 reference

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Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

1 reference

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Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase.

1 reference

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21 January 2018

Specific uncoupling of GRB2 from the Met receptor. Differential effects on transformation and motility

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Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

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A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

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Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

1 reference

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21 January 2018

Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.10772

21 January 2018

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

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Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

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The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

1 reference

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21 January 2018

Regulation of cell growth and motility by hepatocyte growth factor and receptor expression in various cell species

1 reference

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21 January 2018

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

1 reference

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21 January 2018

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

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21 January 2018

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

1 reference

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Migration of 3T3 and lung fibroblasts in response to calcitonin gene-related peptide and bombesin

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Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins.

1 reference

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

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Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.

1 reference

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Rho GTPases and the actin cytoskeleton

1 reference

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The Rap1 GTPase functions as a regulator of morphogenesis in vivo

1 reference

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21 January 2018

Identifiers

10.1074/JBC.275.15.10772

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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