(Q28142396)

1

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E P Garcia

2

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D Dorow

3

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J Marshall

4

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Y F Liu

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

6 April 2001

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published in

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volume

276

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issue

14

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page(s)

11382-6

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cites work

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Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice

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Cloned glutamate receptors

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Kainate receptors: subunits, synaptic localization and function

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Synaptic kainate receptors

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Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95

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Heteromultimerization and NMDA receptor-clustering activity of Chapsyn-110, a member of the PSD-95 family of proteins

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SAP90 binds and clusters kainate receptors causing incomplete desensitization

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Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains

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PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

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Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

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Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

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The stress-activated protein kinase subfamily of c-Jun kinases

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase

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The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

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Activation of MLK2-mediated signaling cascades by polyglutamine-expanded huntingtin

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Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line

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SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

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Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background.

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Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells.

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Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

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Selective loss of [3H]kainic acid and [3H]AMPA binding in layer VI of frontal cortex in Huntington's disease

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Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease

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Genotypes at the GluR6 kainate receptor locus are associated with variation in the age of onset of Huntington disease

21 January 2018

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Overexpression of GluR6 in rat hippocampus produces seizures and spontaneous nonsynaptic bursting in vitro

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