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Genetic analysis of BRCA1 function in a defined tumor cell line
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scholarly article
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title
Genetic analysis of BRCA1 function in a defined tumor cell line
(English)
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main subject
cell line
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author name string
R Scully
series ordinal
1
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S Ganesan
series ordinal
2
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K Vlasakova
series ordinal
3
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J Chen
series ordinal
4
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M Socolovsky
series ordinal
5
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D M Livingston
series ordinal
6
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language of work or name
English
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publication date
December 1999
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published in
Molecular Cell
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volume
4
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page(s)
1093-9
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issue
6
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describes a project that uses
HCC1937
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cites work
BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair
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Induction and rejoining of DNA double-strand breaks and interphase chromosome breaks after exposure to X rays in one normal and two hypersensitive human fibroblast cell lines
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Transcriptional activation by BRCA1
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Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
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Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation
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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
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Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: a closer look
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BRCA1 required for transcription-coupled repair of oxidative DNA damage
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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse
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Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.
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Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.
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Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene
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SYBR Green I staining of pulsed field agarose gels is a sensitive and inexpensive way of quantitating DNA double-strand breaks in mammalian cells
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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
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Evidence for a transcriptional activation function of BRCA1 C-terminal region
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Brca1 controls homology-directed DNA repair
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Structural changes in chromatin as the basis for radiosensitivity in ataxia telangiectasia
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Radiosensitivity in ataxia-telangiectasia: a new explanation
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7 January 2021
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Involvement of Brca2 in DNA repair
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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Location of BRCA1 in human breast and ovarian cancer cells
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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Association of BRCA1 with Rad51 in mitotic and meiotic cells
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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inferred from DOI database lookup
BRCA1 is a component of the RNA polymerase II holoenzyme
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2
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A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.
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7 January 2021
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inferred from DOI database lookup
Relationship between a chromatin anomaly in ataxia-telangiectasia cells and enhanced sensitivity to DNA damage
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The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors
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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction
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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.
1 reference
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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Update on breast cancer susceptibility genes
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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inferred from DOI database lookup
Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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Identification of a RING protein that can interact in vivo with the BRCA1 gene product
1 reference
stated in
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
based on heuristic
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Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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inferred from DOI database lookup
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2980238-5
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7 January 2021
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Identifiers
DOI
10.1016/S1097-2765(00)80238-5
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2963123
OpenCitations bibliographic resource ID
2963123
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2963123
PubMed ID
10635334
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2963123
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