(Q28143185)

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The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction

scientific article (publication date: 16 February 2001)

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scholarly article

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Europe PubMed Central

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1 November 2019

The adapter type protein CMS/CD2AP binds to the proto-oncogenic protein c-Cbl through a tyrosine phosphorylation-regulated Src homology 3 domain interaction (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067845%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

phosphorylation

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Kathrin H Kirsch

1

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1 November 2019

author name string

M M Georgescu

2

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1 November 2019

T Shishido

3

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1 November 2019

W Y Langdon

4

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1 November 2019

R B Birge

5

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1 November 2019

H Hanafusa

6

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publication date

6 November 2000

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1 November 2019

Journal of Biological Chemistry

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1 November 2019

276

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1 November 2019

4957-4963

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1 November 2019

7

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1 November 2019

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Integration of T cell receptor-dependent signaling pathways by adapter proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Focal adhesions - the cytoskeletal connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Integrin signalling: a new Cas(t) of characters enters the stage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

CMS: an adapter molecule involved in cytoskeletal rearrangements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Direct binding of p130(Cas) to the guanine nucleotide exchange factor C3G

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Structural basis for the binding of proline-rich peptides to SH3 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Adapter proteins in lymphocyte antigen-receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Altered composition of the immunological synapse in an anergic, age-dependent memory T cell subset

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Oct-1 protein promotes functional transcription complex assembly on the mouse mammary tumor virus promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Cloning and characterization of a novel adaptor protein, CIN85, that interacts with c-Cbl

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

A novel peptide-SH3 interaction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The cbl oncogene: a novel substrate of protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

The SH3 domain-binding T cell tyrosyl phosphoprotein p120. Demonstration of its identity with the c-cbl protooncogene product and in vivo complexes with Fyn, Grb2, and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M005784200

21 January 2018

Identifiers

10.1074/JBC.M005784200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067845%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11067845%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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