(Q28144249)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10662695%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

The biosynthetic gene cluster for the microtubule-stabilizing agents epothilones A and B from Sorangium cellulosum So ce90 (English)

1 reference

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3 November 2019

0 references

1 reference

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1

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3 November 2019

author name string

T Schupp

2

1 reference

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3 November 2019

M Ono

3

1 reference

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3 November 2019

R Zirkle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10662695%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

M Milnamow

5

1 reference

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3 November 2019

B Nowak-Thompson

6

1 reference

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3 November 2019

N Engel

7

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3 November 2019

C Toupet

8

1 reference

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3 November 2019

A Stratmann

9

1 reference

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3 November 2019

D D Cyr

10

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3 November 2019

J Gorlach

11

1 reference

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3 November 2019

J M Mayo

12

1 reference

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3 November 2019

A Hu

13

1 reference

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3 November 2019

S Goff

14

1 reference

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3 November 2019

J Schmid

15

1 reference

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3 November 2019

J M Ligon

16

1 reference

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3 November 2019

language of work or name

English

0 references

publication date

1 February 2000

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full work available at URL

3 November 2019

http://www.cell.com/article/S1074552100000752/pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(00)00075-2?email=unpaywall_01@example.com

published in

Chemistry and Biology

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3 November 2019

volume

7

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3 November 2019

issue

2

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3 November 2019

page(s)

97-109

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3 November 2019

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1016/s1074-5521(00)00075-2?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

cites work

Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties

1 reference

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7 January 2021

Discodermolide: a new bioactive polyhydroxylated lactone from the marine sponge Discodermia dissoluta

1 reference

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7 January 2021

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Chemical Biology of Epothilones

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Harnessing the biosynthetic code: combinations, permutations, and mutations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

How do peptide synthetases generate structural diversity?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Genetic Contributions to Understanding Polyketide Synthases

1 reference

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7 January 2021

Modular Peptide Synthetases Involved in Nonribosomal Peptide Synthesis

1 reference

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7 January 2021

Multifunctional Peptide Synthetases.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthus codes for a unique PKS module coupled to a peptide synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Two multifunctional peptide synthetases and an O-methyltransferase are involved in the biosynthesis of the DNA-binding antibiotic and antitumour agent saframycin Mx1 from Myxococcus xanthus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Combinatorial biosynthesis for new drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Engineering of modular polyketide synthases to produce novel polyketides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Combinatorial biosynthesis of erythromycin and complex polyketides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Complete nucleotide sequence of two generations of a bacterial artificial chromosome cloning vector.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Cloning and sequence analysis of the putative rifamycin polyketide synthase gene cluster from Amycolatopsis mediterranei

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Rapid restriction mapping of cosmids by sequence-specific triple-helix-mediated affinity capture

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Codon usage in the G+C-rich Streptomyces genome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Thiazole and oxazole peptides: biosynthesis and molecular machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Production of a novel polyketide through the construction of a hybrid polyketide synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A chain initiation factor common to both modular and aromatic polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Iron acquisition in plague: modular logic in enzymatic biogenesis of yersiniabactin by Yersinia pestis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The bacitracin biosynthesis operon of Bacillus licheniformis ATCC 10716: molecular characterization of three multi-modular peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A single amino acid change in AngR, a protein encoded by pJM1-like virulence plasmids, results in hyperproduction of anguibactin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Bleomycin Biosynthesis inStreptomyces verticillusATCC15003: A Model of Hybrid Peptide and Polyketide Biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Characterization of the pyoluteorin biosynthetic gene cluster of Pseudomonas fluorescens Pf-5.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Manipulation of Modular Polyketide Synthases.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

6-Deoxyerythronolide-B synthase 2 from Saccharopolyspora erythraea. Cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Universal catalytic domain structure of AdoMet-dependent methyltransferases.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The Yersiniabactin Biosynthetic Gene Cluster of Yersinia enterocolitica: Organization and Siderophore-Dependent Regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A locus coding for putative non-ribosomal peptide/polyketide synthase functions is mutated in a swarming-defective Proteus mirabilis strain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Structure of cytochrome P450eryF involved in erythromycin biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Metabolic diversity in myxobacteria: identification of the myxalamid and the stigmatellin biosynthetic gene cluster of Stigmatella aurantiaca Sg a15 and a combined polyketide-(poly)peptide gene cluster from the epothilone producing strain Sorangium

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin--nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Sequence around the 159 degree region of the Bacillus subtilis genome: the pksX locus spans 33.6 kb.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Biosynthesis of polyketides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Catalytic self-acylation of type II polyketide synthase acyl carrier proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Lambdoid phages that simplify the recovery of in vitro recombinants

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Acquisition by Escherichia coli of plasmid-borne β-lactamases normally confined to Pseudomonas spp

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Transfer of mobilizable plasmids to Sorangium cellulosum and evidence for their integration into the chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Base-calling of automated sequencer traces using phred. II. Error probabilities

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

Consed: a graphical tool for sequence finishing

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

A comprehensive set of sequence analysis programs for the VAX

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2800%2900075-2

7 January 2021

10.1016/S1074-5521(00)00075-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10662695%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference