(Q28144438)

1

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R N Thorneley

2

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C Abell

3

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S Bornemann

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

17 November 2000

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published in

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volume

275

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issue

46

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page(s)

35825-30

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cites work

A unique reaction in a common pathway: mechanism and function of chorismate synthase in the shikimate pathway

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Chorismate synthase of Neurospora crassa: a flavoprotein

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The overexpression, purification and complete amino acid sequence of chorismate synthase from Escherichia coli K12 and its comparison with the enzyme from Neurospora crassa

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Escherichia coli chorismate synthase

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Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate

21 January 2018

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The transient kinetics of Escherichia coli chorismate synthase: substrate consumption, product formation, phosphate dissociation, and characterization of a flavin intermediate

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A Secondary beta Deuterium Kinetic Isotope Effect in the Chorismate Synthase Reaction

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Substrate analogs as mechanistic probes for the bifunctional chorismate synthase from Neurospora crassa

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Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved

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A continuous, anaerobic spectrophotometric assay for chorismate synthase activity that utilizes photoreduced flavin mononucleotide.

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An improved assay for nanomole amounts of inorganic phosphate

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Preparation, characterization, and chemical properties of the flavin coenzyme analogues 5-deazariboflavin, 5-deazariboflavin 5'-phosphate, and 5-deazariboflavin 5'-diphosphate, 5' → 5'-adenosine ester

21 January 2018

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Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.

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Chorismic acid: purification and some chemical and physical studies

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Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding

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(6S)-6-fluoroshikimic acid, an antibacterial agent acting on the aromatic biosynthetic pathway

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Light-absorption studies on neutral flavin radicals.

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Flavin and 5-deazaflavin: A chemical evaluation of ‘modified’ flavoproteins with respect to the mechanisms of redox biocatalysis

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Binding of the Oxidized, Reduced, and Radical Flavin Species to Chorismate Synthase. An Investigation by Spectrophotometry, Fluorimetry, and Electron Paramagnetic Resonance and Electron Nuclear Double Resonance Spectroscopy†

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Stereochemistry of chorismic acid biosynthesis

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Steric course of the chorismate synthetase reaction and the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase reaction

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Observation of a secondary tritium isotope effect in the chorismate synthase reaction

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Statistical determination of the average values of the extinction coefficients of tryptophan and tyrosine in native proteins

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