(Q28185982)

English

Mechanism, detection and clinical significance of the reciprocal translocation t(12;21)(p12;q22) in the children suffering from acute lymphoblastic leukaemia

scientific article (publication date: 2004)

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Europe PubMed Central

Mechanism, detection and clinical significance of the reciprocal translocation t(12;21)(p12;q22) in the children suffering from acute lymphoblastic leukaemia (English)

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author name string

Małgorzata Sawińska

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Dariusz Ładoń

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language of work or name

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publication date

January 2004

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Leukemia Research

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28

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35-42

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1

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The value of interphase fluorescence in situ hybridization for the detection of translocation t(12;21) in childhood acute lymphoblastic leukemia

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ETV6/AML1 fusion by FISH in adult acute lymphoblastic leukemia

1 reference

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Genomic organization of TEL: the human ETS-variant gene 6.

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7 January 2021

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Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group

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7 January 2021

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ETV6 is the target of chromosome 12p deletions in t(12;21) childhood acute lymphocytic leukemia.

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7 January 2021

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Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party

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Fluorescence in situ hybridization analysis of 12;21 translocation in Japanese childhood acute lymphoblastic leukemia.

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7 January 2021

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Correlation between the ETV6/CBFA2 (TEL/AML1) fusion gene and karyotypic abnormalities in children with B-cell precursor acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Both TEL and AML-1 contribute repression domains to the t(12;21) fusion protein

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1.

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7 January 2021

based on heuristic

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Origins of "late" relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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The der(21)t(12;21) chromosome is always formed in a 12;21 translocation associated with childhood acute lymphoblastic leukaemia

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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TEL is a sequence-specific transcriptional repressor

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

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7 January 2021

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AML1 gene over-expression in childhood acute lymphoblastic leukemia

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7 January 2021

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

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7 January 2021

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Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

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Acute leukemia in children

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7 January 2021

based on heuristic

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The TEL gene products: nuclear phosphoproteins with DNA binding properties

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

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Chromosomal translocations in human cancer.

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7 January 2021

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Relapse of TEL-AML1--positive acute lymphoblastic leukemia in childhood: a matched-pair analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Growth factors and hematopoietic stem cells

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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TEL/AML1 positivity in childhood ALL: average or better prognosis? Czech Paediatric Haematology Working Group

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

TEL-AML1 fusion in acute lymphoblastic leukaemia of adults

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Low frequency of TEL/AML1 in adult acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Low frequency of the TEL/AML1 fusion gene in acute lymphoblastic leukaemia in Spain

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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TEL gene rearrangements in myeloid malignancy

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Specificity within the ets family of transcription factors

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https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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New insights on DNA recognition by ets proteins from the crystal structure of the PU.1 ETS domain-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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The Ets family of transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

1 reference

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7 January 2021

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Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation

1 reference

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7 January 2021

based on heuristic

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Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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A direct physical association between ETS and AP-1 transcription factors in normal human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

High frequency of t(12;21) in childhood acute lymphoblastic leukemia detected by RT-PCR

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Cytogenetic abnormalities associated with the t(12;21): a collaborative study of 169 children with t(12;21)-positive acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

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Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: a molecular cytogenetics study

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

based on heuristic

inferred from DOI database lookup

Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2803%2900160-7

7 January 2021

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10.1016/S0145-2126(03)00160-7

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