(Q28186424)

7 January 2021

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

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7 January 2021

Molecular mechanisms of cytochrome P-450 induction by xenobiotics: An expanded role for nuclear hormone receptors.

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7 January 2021

Humanized xenobiotic response in mice expressing nuclear receptor SXR.

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7 January 2021

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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7 January 2021

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

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7 January 2021

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

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7 January 2021

St John's wort, a herbal antidepressant, activates the steroid X receptor.

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7 January 2021

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

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7 January 2021

Induction of cytochrome P4503A by taxol in primary cultures of human hepatocytes

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7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

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7 January 2021

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

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7 January 2021

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

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7 January 2021

Characterisation of CYP3A gene subfamily expression in human gastrointestinal tissues

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7 January 2021

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

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7 January 2021

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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7 January 2021

Combinatorial roles of the nuclear receptor corepressor in transcription and development

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7 January 2021

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

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7 January 2021

The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT

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7 January 2021

In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients

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7 January 2021

Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743.

1 reference

7 January 2021

Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.

1 reference

7 January 2021

Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

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7 January 2021

Interleukin-6 negatively regulates the expression of pregnane X receptor and constitutively activated receptor in primary human hepatocytes.

1 reference

7 January 2021

Isolation and characterization of a new cDNA clone belonging to the cytochrome P450 2C gene subfamily in hamsters

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7 January 2021

Human cytochrome P450s: selectivity and measurement in vivo

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7 January 2021

Biochemistry and molecular biology of the human CYP2C subfamily

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7 January 2021

The expression of pregnane X receptor and its target gene, cytochrome P450 3A1, in perinatal mouse

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7 January 2021

Clinical pharmacokinetics of docetaxel.

1 reference

7 January 2021

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

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7 January 2021

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

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7 January 2021

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1 reference

7 January 2021