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Gastrointestinal safety of COX-2 specific inhibitors
scientific article (publication date: December 2001)
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scholarly article
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review article
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stated in
Europe PubMed Central
title
Gastrointestinal safety of COX-2 specific inhibitors
(English)
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author name string
C J Hawkey
series ordinal
1
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J I Jones
series ordinal
2
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language of work or name
English
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publication date
December 2001
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published in
Gastroenterology Clinics of North America
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volume
30
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issue
4
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page(s)
921-36
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cites work
Role of Helicobacter pylori in ulcer healing and recurrence of gastric and duodenal ulcers in longterm NSAID users. Response to omeprazole dual therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of nonsteroidal anti-inflammatory drugs on renal function: focus on cyclooxygenase-2-selective inhibition
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Does eradication of Helicobacter pylori impair healing of nonsteroidal anti-inflammatory drug associated bleeding peptic ulcers? A prospective randomized study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Celecoxib: a review of its use in osteoarthritis, rheumatoid arthritis and acute pain
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ranitidine: differential effects on gastric bleeding and mucosal damage induced by aspirin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drug-associated gastropathy: incidence and risk factor models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ocular safety of antiulcer drugs
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Helicobacter pylori and nonsteroidal anti-inflammatory drugs: interaction with proton pump inhibitor therapy for prevention of nonsteroidal anti-inflammatory drug ulcers and ulcer complications--future research needs
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drugs and upper gastrointestinal bleeding, identifying high-risk groups by excess risk estimates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Non-steroidal anti-inflammatory drugs and peptic ulcers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Personal review: Helicobacter pylori, NSAIDs and cognitive dissonance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Outcomes studies of drug induced ulcer complications: do we need them and how should they be done?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Separation of the impairment of haemostasis by aspirin from mucosal injury in the human stomach
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study. Helicobacter Eradication for Lesion Prevention
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiogenesis in gastric ulcers: impaired in patients taking non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of Helicobacter pylori colonisation on gastric mucosal eicosanoid synthesis in patients taking non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of cyclooxygenase 1 and 2 by human gastric endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal consequences of treatment with drugs in elderly patients
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Helicobacter pylori augments the pH-increasing effect of omeprazole in patients with duodenal ulcer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of curing Helicobacter pylori infection on intragastric acidity during treatment with ranitidine in patients with duodenal ulcer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of anti-inflammatory drugs on overall risk of common cancer: case-control study in general practice research database
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific inhibition of cyclooxygenase-2 with MK-0966 is associated with less gastroduodenal damage than either aspirin or ibuprofen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Age does not influence acute aspirin-induced gastric mucosal damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Portal venous transfusion up-regulates Kupffer cell cyclooxygenase activity: a mechanism of immunosuppression in organ transplantation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The discovery of rofecoxib, [MK 966, Vioxx, 4-(4'-methylsulfonylphenyl)-3-phenyl-2(5H)-furanone], an orally active cyclooxygenase-2-inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rofecoxib
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis. A prospective observational cohort study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aspirin, NSAIDs, and digestive tract cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aspirin use and reduced risk of fatal colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative estimation of rare adverse events which follow a biological progression: a new model applied to chronic NSAID use
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peptic ulcer bleeding: accessory risk factors and interactions with non-steroidal anti-inflammatory drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The nonsteroidal anti-inflammatory drugs controversy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs. Acid Suppression Trial: Ranitidine versus Omeprazole for NSAID-associated Ulcer Treatment (ASTRONAUT) Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aspirin protects against gastric cancer: results of a case-control study from Moscow, Russia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0889-8553%2805%2970220-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0889-8553(05)70220-X
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PubMed publication ID
11764535
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