(Q28193702)

2

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Carol Dangelmaier

3

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Robert T Dorsam

4

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Jianguo Jin

5

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James L Daniel

6

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Satya P Kunapuli

Glycoprotein VI-mediated platelet fibrinogen receptor activation occurs through calcium-sensitive and PKC-sensitive pathways without a requirement for secreted ADP

7

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language of work or name

English

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publication date

1 December 2002

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published in

Biochemical Journal

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volume

368

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issue

Pt 2

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page(s)

535-43

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cites work

1 reference

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Identification of the platelet ADP receptor targeted by antithrombotic drugs

20 March 2017

1 reference

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The extended protein kinase C superfamily

20 March 2017

1 reference

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Platelet signal transduction defect with Galpha subunit dysfunction and diminished Galphaq in a patient with abnormal platelet responses

20 March 2017

1 reference

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Evidence for a role for tyrosine phosphorylation of phospholipase C gamma 2 in collagen-induced platelet cytosolic calcium mobilization

20 March 2017

1 reference

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A new generation of Ca2+ indicators with greatly improved fluorescence properties

20 March 2017

1 reference

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Molecular identification and characterization of the platelet ADP receptor targeted by thienopyridine antithrombotic drugs

20 March 2017

1 reference

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Identification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors

20 March 2017

1 reference

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Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C

20 March 2017

1 reference

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The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin

20 March 2017

1 reference

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How the protease thrombin talks to cells

20 March 2017

1 reference

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Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change

29 September 2017

1 reference

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Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

29 September 2017

1 reference

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Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets

29 September 2017

1 reference

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Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets

29 September 2017

1 reference

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Role of platelets in thrombosis and hemostasis.

29 September 2017

1 reference

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Protein kinase C activation is not a key step in ADP-mediated exposure of fibrinogen receptors on human platelets

29 September 2017

1 reference

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Platelet secretion defect associated with impaired liberation of arachidonic acid and normal myosin light chain phosphorylation

29 September 2017

1 reference

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Pharmacological receptors on blood platelets

29 September 2017

1 reference

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Integrin signaling: the platelet paradigm

29 September 2017

1 reference

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Protein kinase C-dependent and -independent mechanisms of dense granule exocytosis by human platelets

2 June 2018

1 reference

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Impaired cytoplasmic ionized calcium mobilization in inherited platelet secretion defects

2 June 2018

1 reference

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Activation of protein kinase C in platelets by epinephrine and A23187: correlation with fibrinogen binding.

2 June 2018

1 reference

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Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the glycoprotein IIB-IIIA complex of human platelets

2 June 2018

1 reference

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Identification and functional characterization of protein kinase C isozymes in platelets and HEL cells

2 June 2018

1 reference

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Regulation of glycoprotein IIB/IIIA exposure on platelets stimulated with alpha-thrombin

2 June 2018

1 reference

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Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors

2 June 2018

1 reference

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Signalling events underlying platelet aggregation induced by the glycoprotein VI agonist convulxin

27 November 2018

1 reference

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Defective platelet activation in G alpha(q)-deficient mice.

27 November 2018

1 reference

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The thrombin receptor in human platelets is coupled to a GTP binding protein of the G alpha q family

27 November 2018

1 reference

12 December 2020

Abnormal inside-out signal transduction-dependent activation of glycoprotein IIb-IIIa in a patient with impaired pleckstrin phosphorylation

1 reference

12 December 2020

Human platelet signaling defect characterized by impaired production of inositol-1,4,5-triphosphate and phosphatidic acid and diminished Pleckstrin phosphorylation: evidence for defective phospholipase C activation

1 reference

12 December 2020

Decreased expression of phospholipase C-beta 2 isozyme in human platelets with impaired function

1 reference

12 December 2020

Signaling through G proteins in platelets: to the integrins and beyond

1 reference

12 December 2020

Differential involvement of tyrosine and serine/threonine kinases in platelet integrin alphaIIbbeta3 exposure

1 reference

12 December 2020

Concomitant activation of Gi and Gq protein-coupled receptors does not require an increase in cytosolic calcium for platelet aggregation

1 reference

12 December 2020

Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets

1 reference

12 December 2020

Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors

1 reference

12 December 2020

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

1 reference

12 December 2020

Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels

1 reference

12 December 2020

Regulation of glycoprotein IIb-IIIa receptor function studied with platelets permeabilized by the pore-forming complement proteins C5b-9

1 reference

12 December 2020

A New Protein Kinase C, nPKCη′, and nPCKθ Are Expressed in Human Platelets: Involvement of nPKCη′ and nPKCθ in Signal Transduction Stimulated by PAF

1 reference

12 December 2020

Exposure of platelet fibrinogen receptors by zinc ions: role of protein kinase C

1 reference

12 December 2020

Concomitant activation of Gi protein-coupled receptor and protein kinase C or phospholipase C is required for platelet aggregation

1 reference

12 December 2020