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Blood substitutes: the future is now
scientific article (publication date: 2003)
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instance of
scholarly article
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title
Blood substitutes: the future is now
(English)
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author name string
Ernest E Moore
series ordinal
1
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language of work or name
English
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publication date
January 2003
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published in
Journal of the American College of Surgeons
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volume
196
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issue
1
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page(s)
1-17
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cites work
Clinical utility of human polymerized hemoglobin as a blood substitute after acute trauma and urgent surgery
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The first randomized trial of human polymerized hemoglobin as a blood substitute in acute trauma and emergent surgery
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Novel treatment modalities: new platelet preparations and substitutes
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Recombinant activated factor VII for adjunctive hemorrhage control in trauma
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Respiratory function of hemoglobin
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The oxyhemoglobin reaction of nitric oxide
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Reactions between nitric oxide and haemoglobin under physiological conditions
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Blood Flow Regulation by S-Nitrosohemoglobin in the Physiological Oxygen Gradient
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Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation
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MAMMALIAN LIFE WITHOUT RED BLOOD CORPUSCLES
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Clinical experience with hemoglobin-saline solutions
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7 January 2021
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The effect of hemoglobin on renal function in the human
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Evaluation of a stroma-free hemoglobin solution for use as a plasma expander
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Further Studies with Stroma-Free Hemoglobin Solution
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Total and partial blood exchange in the rat with hemoglobin prepared by crystallization
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A clinical safety trial of stroma-free hemoglobin
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Large-volume preparation of pyridoxylated hemoglobin with high P50
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A human recombinant haemoglobin designed for use as a blood substitute
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Use of recombinant hemoglobin solution in reversing lethal hemorrhagic hypovolemic oxygen debt shock
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Differences in the Interaction of 2,3-Diphosphoglycerate with Certain Mammalian Hemoglobins
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Efficacy of a new blood substitute based on ultra-pure polymerized bovine hemoglobulin. A preliminary report
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Modification of human hemoglobin with polyethylene glycol : a new candidate for blood substitute
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In vivo evaluation of a pyridoxylated-hemoglobin-polyoxyethylene conjugate.
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A phase I study of oxidized raffinose cross-linked human hemoglobin
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7 January 2021
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Clinical development of human polymerized hemoglobin as a blood substitute
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7 January 2021
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Points to consider in the safety evaluation of hemoglobin-based oxygen carriers. Center for Biologics Evaluation and Research
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Hemoglobin-based blood substitutes: oxygen carriers, pressor agents, or oxidants?
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7 January 2021
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Hemoglobin solutions--not just red blood cell substitutes.
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7 January 2021
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Hemoglobin stimulates the release of proinflammatory cytokines from leukocytes in whole blood
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Points to consider on efficacy evaluation of hemoglobin- and perfluorocarbon-based oxygen carriers. Center for Biologics Evaluation and Research
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Human cardiovascular and metabolic response to acute, severe isovolemic anemia
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Blood Transfusion in Elderly Patients with Acute Myocardial Infarction
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The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study
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7 January 2021
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Effect of blood transfusions on colonic malignancy recurrent rate
1 reference
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reference URL
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7 January 2021
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Blood transfusions and survival after lung cancer resection
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7 January 2021
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Blood transfusion and disease-free survival in carcinoma of the breast
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blood transfusion increases the risk of infection after trauma
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship of transfusion and infection in a burn population.
1 reference
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
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Increased rate of infection associated with transfusion of old blood after severe injury
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
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inferred from DOI database lookup
Mechanisms and new approaches for the allogeneic blood transfusion-induced immunomodulatory effects
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reference URL
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7 January 2021
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inferred from DOI database lookup
Postinjury neutrophil priming and activation states: therapeutic challenges
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Early predictors of postinjury multiple organ failure
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blood transfusion. An independent risk factor for postinjury multiple organ failure.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Postinjury neutrophil priming and activation: an early vulnerable window
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Circulating postinjury neutrophils are primed for the release of proinflammatory cytokines
1 reference
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Leukocyte reduction of blood components: public policy and new technology
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prestorage versus poststorage white cell reduction for the prevention of the deleterious immunomodulatory effects of allogeneic blood transfusion
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Age of transfused blood is an independent risk factor for postinjury multiple organ failure
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
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inferred from DOI database lookup
Time-dependent, spontaneous release of white cell- and platelet-derived bioactive substances from stored human blood
1 reference
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of cytokines in red cell concentrates during storage is prevented by prestorage white cell reduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Blood transfusion and the two-insult model of post-injury multiple organ failure.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Compounds biologically similar to platelet activating factor are present in stored blood components
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transfusion-related acute lung injury: report of a clinical look-back investigation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plasma from aged stored red blood cells delays neutrophil apoptosis and primes for cytotoxicity: abrogation by poststorage washing but not prestorage leukoreduction
1 reference
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of storage on red blood cell rheological properties
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stiffened erythrocytes augment the pulmonary hemodynamic response to hypoxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of stored-blood transfusion on oxygen delivery in patients with sepsis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Failure of red blood cell transfusion to increase oxygen transport or mixed venous PO2 in injured patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock: a randomized controlled efficacy trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Post hoc mortality analysis of the efficacy trial of diaspirin cross-linked hemoglobin in the treatment of severe traumatic hemorrhagic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Systemic and pulmonary hypertension after resuscitation with cell-free hemoglobin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pulmonary hypertension and systemic vasoconstriction may offset the benefits of acellular hemoglobin blood substitutes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resuscitation of pulmonary contusion: effects of a red cell substitute
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initial evaluation of diaspirin cross-linked hemoglobin (DCLHb) as a vasopressor in critically ill patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitric oxide mediates the hypertensive response to a modified hemoglobin solution (DCLHb) in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A first evaluation of the natural high molecular weight polymeric Lumbricus terrestris hemoglobin as an oxygen carrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The reduction of the allogenic transfusion requirement in aortic surgery with a hemoglobin-based solution
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bovine haemoglobin-based oxygen carrier for patients undergoing haemodilution before liver resection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxygen transport by erythrocyte/hemoglobin solution mixtures in an in vitro capillary as a model of hemoglobin-based oxygen carrier performance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bovine hemoglobin increases skeletal muscle oxygenation during 95% artificial arterial stenosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic haemodilution in dogs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bovine hemoglobin-based oxygen carrier (HBOC-201) for resuscitation of uncontrolled, exsanguinating liver injury in swine. Carolina Resuscitation Research Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Limitations of the efficacy of hemoglobin-based oxygen-carrying solutions.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of stroma-free hemoglobin solutions on pulmonary vascular resistance and mediator release in the isolated perfused rabbit lung.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Haemodynamic response following a 10% topload infusion of HemolinkTM in conscious, anaesthetized and treated spontaneously hypertensive rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-free hemoglobin preserves renal function during normothermic ischemia
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Arterial blood pressure responses to cell-free hemoglobin solutions and the reaction with nitric oxide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The development of hemoglobin solutions as red cell substitutes: hemoglobin solutions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resuscitation of the injured patient with polymerized stroma-free hemoglobin does not produce systemic or pulmonary hypertension.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resuscitation with a blood substitute abrogates pathologic postinjury neutrophil cytotoxic function
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
The causes of death in conventional land warfare: implications for combat casualty care research.
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7 January 2021
based on heuristic
inferred from DOI database lookup
Battlefield trauma care: focus on advanced technology
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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Combat casualty management for tomorrow's battlefield: urban terrorism
1 reference
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7 January 2021
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Modeling the consequences of bioterrorism response.
1 reference
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7 January 2021
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Medical management of disasters and mass casualties from terrorist bombings: how can we cope?
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1072-7515%2802%2901704-0
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7 January 2021
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Physical injuries and fatalities resulting from the Oklahoma City bombing
1 reference
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7 January 2021
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A medical disaster response to reduce immediate mortality after an earthquake
1 reference
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7 January 2021
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Transfusions of polymerized bovine hemoglobin in a patient with severe autoimmune hemolytic anemia
1 reference
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7 January 2021
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Blood substitute and erythropoietin therapy in a severely injured Jehovah's witness
1 reference
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7 January 2021
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Prehospital blood transfusion in prolonged evacuation
1 reference
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Crossref
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7 January 2021
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Lessons from everyday lives: a moral justification for acute care research
1 reference
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7 January 2021
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Withholding proven treatment in clinical research
1 reference
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7 January 2021
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Blood substitutes — a moving target
1 reference
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7 January 2021
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Identifiers
DOI
10.1016/S1072-7515(02)01704-0
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PubMed publication ID
12517544
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