(Q28196645)

English

Pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, are not influenced by acetylsalicylic acid

scientific article (publication date: August 2003)

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scholarly article

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Pharmacokinetics and pharmacodynamics of melagatran, the active form of the oral direct thrombin inhibitor ximelagatran, are not influenced by acetylsalicylic acid (English)

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pharmacodynamics

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based on heuristic

inferred from title

pharmacokinetics

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based on heuristic

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author name string

Gunnar Fager

1

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Marie Cullberg

2

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Maria Eriksson-Lepkowska

3

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Lars Frison

4

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Ulf G Eriksson

5

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language of work or name

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publication date

August 2003

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European Journal of Clinical Pharmacology

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59

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4

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283-9

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A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibiti

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin as an antiplatelet drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effect of two low molecular weight thrombin inhibitors and a low-molecular weight heparin in a caval vein thrombosis model in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of melagatran, a novel synthetic LMW thrombin inhibitor, in patients with acute DVT

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adverse interactions between warfarin and nonsteroidal antiinflammatory drugs: mechanisms, clinical significance, and avoidance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of melagatran, a new low-molecular-weight thrombin inhibitor, on thrombin and fibrinolytic enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein binding of aspirin and salicylate measured by in vivo ultrafiltration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct Comparison of Aspirin Plus Hirudin, Aspirin Plus Heparin, and Aspirin Alone Among 12,000 Patients with Acute Myocardial Infarction Not Receiving Thrombolysis: Rationale and Design of the First American Study of Infarct Survival (ASIS-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the oral direct thrombin inhibitor ximelagatran with enoxaparin as prophylaxis against venous thromboembolism after total knee replacement: a phase 2 dose-finding study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retained fibrinolytic response and no coagulation activation after acute physical exercise in middle-aged women with previous myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ximelagatran versus warfarin for the prevention of venous thromboembolism after total knee arthroplasty. A randomized, double-blind trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, controlled, dose-guiding study of the oral direct thrombin inhibitor ximelagatran compared with standard therapy for the treatment of acute deep vein thrombosis: THRIVE I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathobiology of thrombin in acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What effect does controlling platelets have on atherosclerosis?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of melagatran, a novel, direct thrombin inhibitor, in human plasma and urine by liquid chromatography-mass spectrometry.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics, pharmacodynamics and clinical effects of the oral direct thrombin inhibitor ximelagatran in acute treatment of patients with pulmonary embolism and deep vein thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melagatran, an oral active-site inhibitor of thrombin, prevents or delays formation of electrically induced occlusive thrombus in the canine coronary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased risk of intracranial hemorrhage when aspirin is combined with warfarin: A meta-analysis and hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of aspirin against acute myocardial infarction and death in men with unstable angina. Results of a Veterans Administration Cooperative Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of thrombin generation by the oral direct thrombin inhibitor ximelagatran in shed blood from healthy male subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prospective study of the incidence of deep-vein thrombosis within a defined urban population

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral anticoagulant drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombosis in the young: epidemiology and risk factors. A focus on venous thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of the salicylates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12845508

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00228-003-0619-X

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