(Q28199340)

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Real-time kinetics of HIV-1 Rev-Rev response element interactions. Definition of minimal binding sites on RNA and protein and stoichiometric analysis

scientific article (publication date: 18 June 1999)

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scholarly article

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Real-time kinetics of HIV-1 Rev-Rev response element interactions. Definition of minimal binding sites on RNA and protein and stoichiometric analysis (English)

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D I Van Ryk

1

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S Venkatesan

2

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publication date

18 June 1999

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Journal of Biological Chemistry

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274

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25

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17452-63

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Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

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HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.

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21 January 2018

Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes

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21 January 2018

Rev-induced modulation of Nef protein underlies temporal regulation of human immunodeficiency virus replication

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21 January 2018

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA

1 reference

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21 January 2018

Rev and the fate of pre-mRNA in the nucleus: implications for the regulation of RNA processing in eukaryotes

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21 January 2018

A second post-transcriptional trans-activator gene required for HTLV-III replication

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21 January 2018

Expression of the art/trs protein of HIV and study of its role in viral envelope synthesis

1 reference

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21 January 2018

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1 reference

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21 January 2018

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1 reference

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21 January 2018

Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif

1 reference

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21 January 2018

Functional domains of the HIV-1 rev gene required for trans-regulation and subcellular localization

1 reference

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21 January 2018

Specific regulation of mRNA splicing in vitro by a peptide from HIV-1 Rev.

1 reference

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21 January 2018

Identification of trans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells

1 reference

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21 January 2018

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

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21 January 2018

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

1 reference

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21 January 2018

Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast

1 reference

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21 January 2018

A human nucleoporin-like protein that specifically interacts with HIV Rev

1 reference

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21 January 2018

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

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21 January 2018

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

1 reference

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21 January 2018

Evidence for a role of CRM1 in signal-mediated nuclear protein export

1 reference

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21 January 2018

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

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21 January 2018

Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A

1 reference

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21 January 2018

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation

1 reference

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21 January 2018

Intragenic cis-acting art gene-responsive sequences of the human immunodeficiency virus

1 reference

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21 January 2018

Functional analysis of CAR, the target sequence for the Rev protein of HIV-1.

1 reference

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21 January 2018

Specific binding of HIV-1 recombinant Rev protein to the Rev-responsive element in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

Sequence-specific RNA binding by the HIV-1 Rev protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

Secondary structure is the major determinant for interaction of HIV rev protein with RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

1 reference

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21 January 2018

Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

HIV-1 Rev regulation involves recognition of non-Watson-Crick base pairs in viral RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs

1 reference

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21 January 2018

Characterization of HIV-1 REV protein: binding stoichiometry and minimal RNA substrate

1 reference

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21 January 2018

Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.25.17452

21 January 2018

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency

1 reference

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21 January 2018

Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif

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21 January 2018

Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics

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21 January 2018

Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules.

1 reference

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21 January 2018

HIV-1 Rev expressed in recombinant Escherichia coli: purification, polymerization, and conformational properties

1 reference

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21 January 2018

Purification of biologically active human immunodeficiency virus rev protein from Escherichia coli

1 reference

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21 January 2018

Determination of rate and equilibrium binding constants for macromolecular interactions using surface plasmon resonance: use of nonlinear least squares analysis methods.

1 reference

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21 January 2018

A structural model for the HIV-1 Rev-RRE complex deduced from altered-specificity rev variants isolated by a rapid genetic strategy

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21 January 2018

Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production

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21 January 2018

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

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DNA binding of the lac repressor

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21 January 2018

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency

1 reference

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21 January 2018

The amino terminal domain of HIV-1 Rev is required for discrimination of the RRE from nonspecific RNA.

1 reference

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21 January 2018

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1 reference

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21 January 2018

Mutants in a conserved region near the carboxy-terminus of HIV-1 Rev identify functionally important residues and exhibit a dominant negative phenotype

1 reference

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21 January 2018

A molecular rheostat. Co-operative rev binding to stem I of the rev-response element modulates human immunodeficiency virus type-1 late gene expression

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21 January 2018

Analysis of mass transport-limited binding kinetics in evanescent wave biosensors

1 reference

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21 January 2018

Perturbation of the carboxy terminus of HIV-1 Rev affects multimerization on the Rev responsive element

1 reference

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21 January 2018

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10.1074/JBC.274.25.17452

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