(Q28201137)

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Synthesizing life

scientific article (publication date: 18 January 2001)

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Synthesizing life (English)

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J W Szostak

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D P Bartel

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P L Luisi

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publication date

18 January 2001

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409

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6818

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387-90

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Global transposon mutagenesis and a minimal Mycoplasma genome

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Origin of life: The RNA world

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About various definitions of life

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Ribozymes: aiming at RNA replication and protein synthesis

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Constructing an RNA world

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RNA-catalysed synthesis of complementary-strand RNA

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Selection of a ribozyme that functions as a superior template in a self-copying reaction

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Isolation of new ribozymes from a large pool of random sequences [see comment]

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Structurally complex and highly active RNA ligases derived from random RNA sequences

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The secondary structure and sequence optimization of an RNA ligase ribozyme

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Kinetic framework for ligation by an efficient RNA ligase ribozyme

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RNA-catalysed RNA polymerization using nucleoside triphosphates

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A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis

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Evolution of the RNA coliphages: the role of secondary structures during RNA replication

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Matrix Effect in the Size Distribution of Fatty Acid Vesicles

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Autopoietic Self-Reproduction of Fatty Acid Vesicles

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Studies on the mechanism of membrane fusion: kinetics of calcium ion induced fusion of phosphatidylserine vesicles followed by a new assay for mixing of aqueous vesicle contents

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H+- and Ca2+-induced fusion and destabilization of liposomes.

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A fission-fusion origin for life

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Autocatalytic self-replicating micelles as models for prebiotic structures

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Production of RNA by a polymerase protein encapsulated within phospholipid vesicles

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Oparin's Reactions Revisited: Enzymic Synthesis of Poly(adenylic acid) in Micelles and Self-Reproducing Vesicles

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Partition behavior of a nonionic detergent, octyl glucoside, between membrane and water phases, and its effect on membrane permeability

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Effects of submicellar bile salt concentrations on biological membrane permeability to low molecular weight non-ionic solutes

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Polymerase chain reaction in liposomes

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RNAs that bind and change the permeability of phospholipid membranes

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