(Q28202676)

English

Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters

scientific article (publication date: December 2001)

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scholarly article

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Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters (English)

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Stephen M. Husbands

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ORCID Public Data File 2021

author name string

R R Matsumoto

1

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K L Hewett

2

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B Pouw

3

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W D Bowen

4

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S M Husbands

5

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J J Cao

6

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A H Newman

7

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language of work or name

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publication date

December 2001

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Neuropharmacology

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41

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7

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878-86

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Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.

1 reference

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7 January 2021

Rimcazole, a sigma receptor ligand, and the anticonvulsive action of conventional antiepileptic drugs.

1 reference

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7 January 2021

Prevention of cocaine-induced convulsions and lethality in mice: effectiveness of targeting different sites on the NMDA receptor complex

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7 January 2021

Pharmacotherapies for treatment of cocaine abuse: preclinical aspects

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Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

1 reference

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7 January 2021

Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brain

1 reference

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7 January 2021

Highly potent cocaine analogs cause long-lasting increases in locomotor activity.

1 reference

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7 January 2021

Isothiocyanate derivatives of 9-[3-(cis-3,5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole): irreversible ligands for the dopamine transporter

1 reference

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7 January 2021

Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues

1 reference

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7 January 2021

Cocaine and several sigma receptor ligands inhibit dopamine uptake in rat caudate-putamen.

1 reference

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Effects of rimcazole, a specific antagonist of sigma sites, on the antitussive effects of non-narcotic antitussive drugs

1 reference

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7 January 2021

The dopamine hypothesis of the reinforcing properties of cocaine

1 reference

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Metaphit-induced audiogenic seizures in mice: II. Studies on N-methyl-D-aspartic acid, GABA, and sodium channel receptors and on the disposition of metaphit in the brain.

1 reference

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7 January 2021

Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine

1 reference

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7 January 2021

Correlation between neuroleptic binding to sigma(1) and sigma(2) receptors and acute dystonic reactions

1 reference

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7 January 2021

Dissociation of the motor effects of (+)-pentazocine from binding to sigma 1 sites

1 reference

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7 January 2021

Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice

1 reference

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7 January 2021

N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice

1 reference

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7 January 2021

Two novel sigma receptor ligands, BD1047 and LR172, attenuate cocaine-induced toxicity and locomotor activity

1 reference

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7 January 2021

Selective sigma ligands block stimulant effects of cocaine.

1 reference

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7 January 2021

Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.

1 reference

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7 January 2021

Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene

1 reference

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7 January 2021

Cocaine toxicity: concurrent influence of dopaminergic, muscarinic and sigma receptors in mediating cocaine-induced lethality.

1 reference

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7 January 2021

[3H]WIN 35,065-2: a ligand for cocaine receptors in striatum

1 reference

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7 January 2021

Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference

1 reference

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Cloning and functional characterization of a sigma receptor from rat brain.

1 reference

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7 January 2021

Cocaine binding at sigma receptors.

1 reference

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7 January 2021

Cocaine reward models: conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice

1 reference

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7 January 2021

sigma Receptor antagonists block the development of sensitization to cocaine.

1 reference

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7 January 2021

Cocaine: evidence for NMDA-, beta-carboline- and dopaminergic-mediated seizures in mice

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Pharmacological characteristics and distributions of sigma- and phencyclidine receptors in the animal kingdom

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Addictive Drugs and Brain Stimulation Reward

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7 January 2021

Blockade of the locomotor stimulant effects of cocaine and methamphetamine by glutamate antagonists.

1 reference

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7 January 2021

Subchronic administration of N-[2-(3,4-dichlorophenyl) ethyl]-N-methyl-2-(dimethylamino) ethylamine (BD1047) alters sigma 1 receptor binding.

1 reference

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7 January 2021

Antidepressant drugs appear to enhance cocaine-induced toxicity

1 reference

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7 January 2021

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10.1016/S0028-3908(01)00116-2

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