(Q28202989)

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A phosphorylation-driven ubiquitination switch for cell-cycle control

scientific article (publication date: March 2002)

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title

A phosphorylation-driven ubiquitination switch for cell-cycle control (English)

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main subject

protein ubiquitination

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J Wade Harper

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language of work or name

English

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publication date

March 2002

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published in

Trends in Cell Biology

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volume

12

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issue

3

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page(s)

104-7

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cites work

Building a cellular switch: more lessons from a good egg.

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

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The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

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How the cyclin became a cyclin: regulated proteolysis in the cell cycle

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SCF and Cullin/Ring H2-based ubiquitin ligases

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

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Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

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7 January 2021

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

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7 January 2021

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Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

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Rapid degradation of the G1 cyclin Cln2 induced by CDK-dependent phosphorylation

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Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex

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Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase

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7 January 2021

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

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reference URL

https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902238-3

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7 January 2021

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Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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7 January 2021

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

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Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

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7 January 2021

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Mitotic treasures in the nucleolus

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902238-3

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7 January 2021

based on heuristic

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Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex

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https://api.crossref.org/works/10.1016%2FS0962-8924%2801%2902238-3

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7 January 2021

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Identifiers

DOI

10.1016/S0962-8924(01)02238-3

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PubMed publication ID

11859016

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(Q28202989)

A phosphorylation-driven ubiquitination switch for cell-cycle control

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