(Q28204014)

English

Substitution of Cysteine for Selenocysteine in the Catalytic Center of Type III Iodothyronine Deiodinase Reduces Catalytic Efficiency and Alters Substrate Preference

scientific article (publication date: June 2003)

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scholarly article

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Substitution of cysteine for selenocysteine in the catalytic center of type III iodothyronine deiodinase reduces catalytic efficiency and alters substrate preference (English)

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Substitution of Cysteine for Selenocysteine in the Catalytic Center of Type III Iodothyronine Deiodinase Reduces Catalytic Efficiency and Alters Substrate Preference (English)

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

L-selenocysteine

1 reference

based on heuristic

inferred from title

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

author name string

Willem Klootwijk

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George G. J M. Kuiper

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12746313

2 January 2024

Theo J. Visser

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12746313

2 January 2024

language of work or name

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publication date

June 2003

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full work available at URL

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144

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6

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2505-13

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SV40-transformed simian cells support the replication of early SV40 mutants

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0092-8674(81)90282-8

Iodothyronine deiodinases

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

The deiodinase family of selenoproteins

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10.1210/EN.2003-0084

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2 January 2024

Pathways of thyroid hormone metabolism.

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10.1210/EN.2003-0084

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2 January 2024

Phenolic and tyrosyl ring deiodination of iodothyronines in rat brain homogenates

6

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Characteristics of iodothyronine tyrosyl ring deiodination by rat cerebral cortical microsomes.

7

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10.1210/EN.2003-0084

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2 January 2024

The Effects of Propylthiouracil, Iodothyronines, and Other Agents on Thyroid Hormone Metabolism in Human Placenta*

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

The ontogeny of iodothyronine deiodinase systems in liver and intestine of the rat.

9

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10.1210/EN.2003-0084

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2 January 2024

Pregnant rat uterus expresses high levels of the type 3 iodothyronine deiodinase

10

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Expression profiles of the three iodothyronine deiodinases, D1, D2, and D3, in the developing rat.

11

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Evidence for a role of the type III-iodothyronine deiodinase in the regulation of 3,5,3'-triiodothyronine content in the human central nervous system

13

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Placental iodothyronine deiodinase III and II ratios, mRNA expression compared to enzyme activity

14

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Induction of thyroid hormone-degrading deiodinase in cardiac hypertrophy and failure

15

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10.1210/EN.2003-0084

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2 January 2024

Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase

19

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Asymmetric growth and development of the Xenopus laevis retina during metamorphosis is controlled by type III deiodinase

20

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Thyroid hormone deiodination pathways in brain and liver of rainbow trout, Oncorhynchus mykiss.

23

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Severe hypothyroidism caused by type 3 iodothyronine deiodinase in infantile hemangiomas

24

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Development effects of thyroid hormone: the role of deiodinases in regulatory control

25

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Regulation of thyroid hormone metabolism during fetal development

26

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10.1210/EN.2003-0084

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2 January 2024

Is neuropsychological development related to maternal hypothyroidism or to maternal hypothyroxinemia?

27

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Type 3 Iodothyronine Deiodinase Is Selectively Expressed in Areas Related to Sexual Differentiation in the Newborn Rat Brain

28

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Action of thyroid hormone in brain

29

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Evidence that type III iodothyronine deiodinase in rat astrocyte is a selenoprotein

30

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Effects of selenium deficiency on tissue selenium content, deiodinase activity, and thyroid hormone economy in the rat during development

31

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

A thyroid hormone-regulated gene in Xenopus laevis encodes a type III iodothyronine 5-deiodinase

32

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Cloning and expression of a cDNA for a mammalian type III iodothyronine deiodinase

33

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Type 3 lodothyronine deiodinase: cloning, in vitro expression, and functional analysis of the placental selenoenzyme

34

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Decoding apparatus for eukaryotic selenocysteine insertion

37

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex

38

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Reactions of Organoselenenyl Iodides with Thiouracil Drugs: An Enzyme Mimetic Study on the Inhibition of Iodothyronine Deiodinase

39

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor

40

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Substitution of cysteine for selenocysteine in type I iodothyronine deiodinase reduces the catalytic efficiency of the protein but enhances its translation

41

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Radioimmunoassay of reverse tri-iodothyronine

43

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Inactivation and affinity-labeling of rat liver iodothyronine deiodinase with N-bromoacetyl-3,3',5-triiodothyronine

44

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Miniprep DNA isolation for automated sequencing of multiple samples

46

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10.1210/EN.2003-0084

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2 January 2024

Luminography - a new, highly sensitive visualization method for electrophoresis

48

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Synthesis and properties of N-bromoacetyl-L-thyroxine

49

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Species differences in liver type I iodothyronine deiodinase

50

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Investigation of type I and type III iodothyronine deiodinases in rat tissues using N-bromoacetyl-iodothyronine affinity labels

51

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Reaction of the type III iodothyronine deiodinase with the affinity label N-bromoacetyl-triiodothyronine

52

1 reference

10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

53

1 reference

10.1210/EN.2003-0084

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2 January 2024

Purification and properties of a recombinant sulfur analog of murine selenium-glutathione peroxidase

54

1 reference

10.1210/EN.2003-0084

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2 January 2024

Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

55

1 reference

10.1210/EN.2003-0084

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2 January 2024

Catalytic properties of an Escherichia coli formate dehydrogenase mutant in which sulfur replaces selenium

56

1 reference

10.1210/EN.2003-0084

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2 January 2024

Comparison of the chemical properties of selenocysteine and selenocystine with their sulfur analogs

57

1 reference

10.1210/EN.2003-0084

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2 January 2024

Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations

58

1 reference

10.1210/EN.2003-0084

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2 January 2024

Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity

59

1 reference

10.1210/EN.2003-0084

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2 January 2024

The crystal structure of seleno-glutathione peroxidase from human plasma at 2.9 A resolution

62

1 reference

10.1210/EN.2003-0084

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2 January 2024

Modification of rat liver iodothyronine 5'-deiodinase activity with diethylpyrocarbonate and rose bengal; evidence for an active site histidine residue

63

1 reference

10.1210/EN.2003-0084

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2 January 2024

Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes

68

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10.1210/EN.2003-0084

https://api.crossref.org/works/10.1210/EN.2003-0084

2 January 2024

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10.1210/EN.2003-0084

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