(Q28204837)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Dysregulated ryanodine receptors mediate cellular toxicity: restoration of normal phenotype by FKBP12.6. (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

John Mackrill

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Tony Lai

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

Gemma V Higgs

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

language of work or name

English

0 references

publication date

16 May 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

3 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

28856-28864

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

The versatility and universality of calcium signalling

3 November 2019

cites work

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Cardiac intracellular calcium release channels: role in heart failure

21 January 2018

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Serum-activated assembly and membrane translocation of an endogenous Rac1:effector complex

21 January 2018

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

21 January 2018

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Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway

21 January 2018

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Control of apoptosis by IP(3) and ryanodine receptor driven calcium signals

21 January 2018

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SR compartment calcium and cell apoptosis in SERCA overexpression

21 January 2018

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Depletion of intracellular calcium stores is toxic to SH-SY5Y neuronal cells

21 January 2018

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The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

21 January 2018

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Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

21 January 2018

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Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

21 January 2018

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Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca(2+) signals.

21 January 2018

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T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

21 January 2018

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Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death.

21 January 2018

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Regulation of cardiac muscle Ca2+ release channel by sarcoplasmic reticulum lumenal Ca2+

21 January 2018

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Regulation of ryanodine receptor opening by lumenal Ca(2+) underlies quantal Ca(2+) release in PC12 cells.

21 January 2018

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Ca(2+)-sensor region of IP(3) receptor controls intracellular Ca(2+) signaling

21 January 2018

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Protein-protein interactions in intracellular Ca2+-release channel function.

21 January 2018

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Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides

21 January 2018

1 reference

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PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

21 January 2018

1 reference

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In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6

21 January 2018

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The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis

21 January 2018

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Differential expression and regulation of ryanodine receptor and myo-inositol 1,4,5-trisphosphate receptor Ca2+ release channels in mammalian tissues and cell lines

21 January 2018

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Analysis of type 1 ryanodine receptor-12 kDa FK506-binding protein interaction.

21 January 2018

1 reference

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Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes

21 January 2018

1 reference

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Heterotetrameric complex formation of inositol 1,4,5-trisphosphate receptor subunits

21 January 2018

1 reference

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Regulation of phosphoinositide-specific phospholipase C

21 January 2018

1 reference

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Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

21 January 2018

1 reference

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Expression and functional characterization of the cardiac muscle ryanodine receptor Ca(2+) release channel in Chinese hamster ovary cells

21 January 2018

1 reference

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Measurement of resting cytosolic Ca2+ concentrations and Ca2+ store size in HEK-293 cells transfected with malignant hyperthermia or central core disease mutant Ca2+ release channels.

21 January 2018

1 reference

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FKBP12 associates tightly with the skeletal muscle type 1 ryanodine receptor, but not with other intracellular calcium release channels.

21 January 2018

1 reference

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Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy

21 January 2018

1 reference

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FKBP12.6-mediated stabilization of calcium-release channel (ryanodine receptor) as a novel therapeutic strategy against heart failure

21 January 2018

1 reference

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FKBP binding characteristics of cardiac microsomes from diverse vertebrates

21 January 2018

1 reference

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Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

21 January 2018

1 reference

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Effects of BAPTA-AM, Forskolin, DSF and Z.VAD.fmk on PDT-induced apoptosis and m-THPC phototoxicity on B16 cells

21 January 2018

1 reference

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Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum

21 January 2018

1 reference

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Carbachol triggers RyR-dependent Ca(2+) release via activation of IP(3) receptors in isolated rat gastric myocytes

21 January 2018

1 reference

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Cellular distribution of Ca2+ pumps and Ca2+ release channels in rat cardiac hypertrophy induced by aortic stenosis

21 January 2018

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Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons

21 January 2018

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Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells

21 January 2018

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Depletion of intracellular Ca2+ by caffeine and ryanodine induces apoptosis of chinese hamster ovary cells transfected with ryanodine receptor

21 January 2018

1 reference

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Altered stoichiometry of FKBP12.6 versus ryanodine receptor as a cause of abnormal Ca(2+) leak through ryanodine receptor in heart failure

21 January 2018

1 reference

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Fluorescent Methods for Measuring and Imaging Cytosolic Free Ca2+ in Neutrophils

21 January 2018

1 reference

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Selective binding of FKBP12.6 by the cardiac ryanodine receptor

21 January 2018

1 reference

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Effects of rapamycin on ryanodine receptor/Ca(2+)-release channels from cardiac muscle

21 January 2018

1 reference

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Enhanced phosphorylation of phospholamban and downregulation of sarco/endoplasmic reticulum Ca2+ ATPase type 2 (SERCA 2) in cardiac sarcoplasmic reticulum from rabbits with heart failure

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M212440200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12754204%20AND%20SRC:MED&resulttype=core&format=json

release_aom5xmcgbfb6jpkg42lbb6k2cm

3 November 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/aom5xmcgbfb6jpkg42lbb6k2cm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference