(Q28204871)

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O Daumke

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E V Deverson

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J C Howard

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M R Knittler

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

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language of work or name

English

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publication date

20 February 2001

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published in

Current Biology

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volume

11

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issue

4

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page(s)

242-51

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cites work

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7 January 2021

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

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ABC Transporters: From Microorganisms to Man

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Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP

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7 January 2021

A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes

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7 January 2021

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly

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Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains

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The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

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Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules

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ATPase activity and ATP/ADP-induced conformational change in the soluble domain of the bacterial protein translocator HlyB

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Secondary and tertiary structure changes of reconstituted P-glycoprotein. A Fourier transform attenuated total reflection infrared spectroscopy analysis

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Conformational changes of P-glycoprotein by nucleotide binding

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Role of nucleotides and peptide substrate for stability and functional state of the human ABC family transporters associated with antigen processing.

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Peptide-bound major histocompatibility complex class I molecules associate with tapasin before dissociation from transporter associated with antigen processing

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The P-loop--a common motif in ATP- and GTP-binding proteins

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Structurally and catalytically important residues in the phosphate binding loop of adenylate kinase of Escherichia coli.

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Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

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Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses

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Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein

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Both ATP sites of human P-glycoprotein are essential but not symmetric

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Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)

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Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains

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Nonequivalence of the nucleotide-binding subunits of an ABC transporter, the histidine permease, and conformational changes in the membrane complex

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Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

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ATP hydrolysis cycles and mechanism in P-glycoprotein and CFTR.

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Human transporters associated with antigen processing possess a promiscuous peptide-binding site

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7 January 2021

The major substrates for TAP in vivo are derived from newly synthesized proteins

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Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

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MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding

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Major histocompatibility complex class I molecules interact with both subunits of the transporter associated with antigen processing, TAP1 and TAP2.

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Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased ex

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Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen presentation

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MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters.

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Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter

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A human beta-actin expression vector system directs high-level accumulation of antisense transcripts

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7 January 2021

Walker A lysine mutations of TAP1 and TAP2 interfere with peptide translocation but not peptide binding.

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7 January 2021