(Q28212325)

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

24 March 2024

author name string

Eugene Krynetski

1

0 references

William E. Evans

2

1 reference

Europe PubMed Central

PubMed publication ID

14576848

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576848

full work available at URL

24 March 2024

language of work or name

English

0 references

publication date

20 October 2003

0 references

https://www.nature.com/articles/1206944.pdf

file format

Portable Document Format

online access status

open access

1 reference

Europe PubMed Central

PubMed publication ID

14576848

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576848

https://www.nature.com/articles/1206944.pdf

24 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

https://www.nature.com/articles/1206944

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

24 March 2024

0 references

22

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issue

47

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page(s)

7403-13

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cites work

Influence of the variable number of tandem repeats located in the promoter region of the thiopurine methyltransferase gene on enzymatic activity

1 reference

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Genetic polymorphisms of thiopurine S-methyltransferase and 6-mercaptopurine toxicity in Japanese children with acute lymphoblastic leukaemia

21 January 2018

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6-thioguanine resistance in a human colon carcinoma cell line with unaltered levels of hypoxanthine guanine phosphoribosyltransferase activity

21 January 2018

1 reference

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Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine

21 January 2018

1 reference

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Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

21 January 2018

1 reference

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Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

21 January 2018

1 reference

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A tellurite-resistance genetic determinant from phytopathogenic pseudomonads encodes a thiopurine methyltransferase: evidence of a widely-conserved family of methyltransferases.

21 January 2018

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Nobel lecture in physiology or medicine--1988. The purine path to chemotherapy.

21 January 2018

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Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

21 January 2018

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Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia

21 January 2018

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Pharmacogenomics--drug disposition, drug targets, and side effects

21 January 2018

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Molecular cloning and functional characterization of the cDNA encoding the murine thiopurine S-methyltransferase (TPMT)

21 January 2018

1 reference

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Functional characterization of the human thiopurine S-methyltransferase (TPMT) gene promoter.

21 January 2018

1 reference

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Mitochondrial genome variation and the origin of modern humans

21 January 2018

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Pharmacogenetics of cancer therapy: getting personal

21 January 2018

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Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance

21 January 2018

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21 January 2018

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A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

21 January 2018

1 reference

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Frequencies of thiopurine S-methyltransferase mutant alleles (TPMT*2, *3A, *3B and *3C) in 151 healthy Japanese subjects and the inheritance of TPMT*3C in the family of a propositus

21 January 2018

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Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese

21 January 2018

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Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations

21 January 2018

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Escherichia coli TehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance

21 January 2018

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Detection of one single mutation predicts thiopurine S-methyltransferase activity in a population of Saami in northern Norway

21 January 2018

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Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Thiopurine methyltransferase activity in the Jewish population of Israel

21 January 2018

1 reference

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Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

21 January 2018

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Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.

21 January 2018

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Regulation of protein degradation rates in eukaryotes

21 January 2018

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Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms

21 January 2018

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Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity

21 January 2018

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Thiopurine methyltransferase activity in a Korean population sample of children.

21 January 2018

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Methylation of inorganic and organic selenium by the bacterial thiopurine methyltransferase.

21 January 2018

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Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

High incidence of secondary brain tumours after radiotherapy and antimetabolites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Detection of known and new mutations in the thiopurine S-methyltransferase gene by single-strand conformation polymorphism analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Childhood hyperuricemia and acute renal failure resulting from a missense mutation in the HPRT gene

21 January 2018

1 reference

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Thiopurine methyltransferase pharmacogenetics: human gene cloning and characterization of a common polymorphism

21 January 2018

1 reference

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Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity

21 January 2018

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The COG database: new developments in phylogenetic classification of proteins from complete genomes

21 January 2018

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Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

21 January 2018

1 reference

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Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Human kidney thiopurine methyltransferase. Purification and biochemical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Thiopurine methyltransferase polymorphic tandem repeat: genotype-phenotype correlation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

21 January 2018

1 reference

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6-Methylthioguanylic acid, a metabolite of 6-thioguanine

21 January 2018

1 reference

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7 January 2021

Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene.

1 reference

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7 January 2021

A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Purification and properties of 5-phosphoribosyl pyrophosphate amidotransferase from adenocarcinoma 755 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Molecular haplotyping of genomic DNA for multiple single-nucleotide polymorphisms located kilobases apart using long-range polymerase chain reaction and intramolecular ligation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Thiopurine methyltransferase activity in American white subjects and black subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206944

7 January 2021

Purine substrates for human thiopurine methyltransferase

13

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese

24 March 2024

26

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

Hypoxanthine-guanine phosphoribosyl-transferase in childhood leukemia: relation with immunophenotype, in vitro drug resistance and clinical prognosis

24 March 2024

52

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.

24 March 2024

66

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

Thiopurine methyltransferase biochemical genetics: human lymphocyte activity

24 March 2024

75

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206944

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

24 March 2024

81

1 reference

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