(Q28214653)

English

A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1

scientific article (publication date: 19 July 2002)

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scholarly article

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A point mutation of the AF2 transactivation domain of the glucocorticoid receptor disrupts its interaction with steroid receptor coactivator 1 (English)

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author name string

Tomas Kucera

1

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Mary Waltner-Law

2

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Donald K Scott

3

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Ratna Prasad

4

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Daryl K Granner

5

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language of work or name

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publication date

19 July 2002

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Journal of Biological Chemistry

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277

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29

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26098-102

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Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene

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The steroid and thyroid hormone receptor superfamily

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Cooperative and positional independent trans-activation domains of the human glucocorticoid receptor.

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Functional domains of the human glucocorticoid receptor

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Primary structure and expression of a functional human glucocorticoid receptor cDNA

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Multiple and cooperative trans-activation domains of the human glucocorticoid receptor

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Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription

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AF-2-dependent potentiation of CCAAT enhancer binding protein beta-mediated transcriptional activation by glucocorticoid receptor

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Direct interaction of the tau 1 transactivation domain of the human glucocorticoid receptor with the basal transcriptional machinery

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Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor

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Glucocorticoid receptor phosphorylation: overview, function and cell cycle-dependence.

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Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene

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Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

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SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

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Activation of the phosphoenolpyruvate carboxykinase gene retinoic acid response element is dependent on a retinoic acid receptor/coregulator complex

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Three amino acid substitutions selectively disrupt the activation but not the repression function of the glucocorticoid receptor N terminus.

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Point Mutation in the Ligand-Binding Domain of the Progesterone Receptor Generates a Transdominant Negative Phenotype

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Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene

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Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoids

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Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

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The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT

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Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor

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Structure/Function of the Human Glucocorticoid Receptor: Tyrosine 735 Is Important for Transactivation

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The Phosphoenolpyruvate Carboxykinase Gene Glucocorticoid Response Unit: Identification of the Functional Domains of Accessory Factors HNF3 (Hepatic Nuclear Factor-3 ) and HNF4 and the Necessity of Proper Alignment of Their Cognate Binding Sites

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Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

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Role of acidic and phosphorylated residues in gene activation by the glucocorticoid receptor

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Interdomain signaling in a two-domain fragment of the human glucocorticoid receptor

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The seven amino acids (547-553) of rat glucocorticoid receptor required for steroid and hsp90 binding contain a functionally independent LXXLL motif that is critical for steroid binding

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Accessory factors facilitate the binding of glucocorticoid receptor to the phosphoenolpyruvate carboxykinase gene promoter

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10.1074/JBC.M204013200

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