(Q28214754)

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Genetic instability in human mismatch repair deficient cancers

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Europe PubMed Central

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Genetic instability in human mismatch repair deficient cancers (English)

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Alex Duval

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Richard Hamelin

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2

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English

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2002

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45

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71-5

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2

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Clues to the pathogenesis of familial colorectal cancer

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Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers.

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Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy

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Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

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Frameshift mutator mutations

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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Gender difference for mismatch repair deficiency in human colorectal cancer

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A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype

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Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

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Microsatellite instability in cancer of the proximal colon

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CpG island methylator phenotype in colorectal cancer

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Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

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10.1016/S0003-3995(02)01115-2

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12119215

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(Q28214754)

Genetic instability in human mismatch repair deficient cancers

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