(Q28215731)

12 December 2020

Does pregnancy immunize against breast cancer?

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12 December 2020

Tumor-specific cytotoxic T cell clones from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin complementary DNA.

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12 December 2020

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

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12 December 2020

Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components

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12 December 2020

Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope

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12 December 2020

ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

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12 December 2020

Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer

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12 December 2020

Electron-microscopic studies of the CA antigen, epitectin

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12 December 2020

Murine immune response to cells transfected with human MUC1: immunization with cellular and synthetic antigens

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12 December 2020

Episialin (MUC1) inhibits cytotoxic lymphocyte-target cell interaction

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12 December 2020

MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma

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12 December 2020

Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours

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12 December 2020

Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients

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12 December 2020

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells

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12 December 2020

Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer

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12 December 2020

Survival in early breast cancer patients is favorably influenced by a natural humoral immune response to polymorphic epithelial mucin.

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12 December 2020

Biophysical characterization of one-, two-, and three-tandem repeats of human mucin (muc-1) protein core

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12 December 2020

Suppression of cellular aggregation by high levels of episialin

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12 December 2020

MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets

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12 December 2020

Expression of MUC-1 epitopes on normal bone marrow: implications for the detection of micrometastatic tumor cells

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12 December 2020

MUC1: the polymorphic appearance of a human mucin

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12 December 2020

Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines

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12 December 2020

Secreted MUC1 mucins lacking their cytoplasmic part and carrying sialyl-Lewis a and x epitopes from a tumor cell line and sera of colon carcinoma patients can inhibit HL-60 leukocyte adhesion to E-selectin-expressing endothelial cells

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12 December 2020

Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells

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12 December 2020

Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells

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12 December 2020

Recruitment of helper T cells for induction of tumour rejection by cytolytic T lymphocytes

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12 December 2020

The breast cancer-associated MUC1 gene generates both a receptor and its cognate binding protein

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12 December 2020

The EGF receptor: a nexus for trafficking and signaling

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12 December 2020

Analysis of the tissue-specific promoter of the MUC1 gene.

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12 December 2020

A gene dosage effect is responsible for high overexpression of the MUC1 gene observed in human breast tumors

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12 December 2020

Cell-associated episialin is a complex containing two proteins derived from a common precursor

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12 December 2020

Characterization of cis-acting elements regulating transcription of the human DF3 breast carcinoma-associated antigen (MUC1) gene

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12 December 2020

Distinct sub-populations of carcinoma-associated MUC1 mucins as detected by the monoclonal antibody 9H8 and antibodies against the sialyl-Lewis a and sialyl-Lewis x epitopes in the circulation of breast-cancer patients

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12 December 2020

Humoral immune response to polymorphic epithelial mucin (MUC-1) in patients with benign and malignant breast tumours

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12 December 2020

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas

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12 December 2020

Expression of MUC1 mucin on activated human T cells: implications for a role of MUC1 in normal immune regulation

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12 December 2020

Effect of modification of carbohydrate side chains on the reactivity of antibodies with core-protein epitopes of the MUC1 gene product.

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12 December 2020

Altered glycosylation of the MUC-1 protein core contributes to the colon carcinoma-associated increase of mucin-bound sialyl-Lewis(x) expression.

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12 December 2020

An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

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12 December 2020

Effect of interferon-gamma and TNF-alpha on MUC1 mucin expression in ovarian carcinoma cell lines

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12 December 2020

Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion

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12 December 2020

Prognostic significance of MUC1 epithelial mucin expression in breast cancer

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12 December 2020

High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells

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12 December 2020

A nuclear factor that binds purine-rich, single-stranded oligonucleotides derived from S1-sensitive elements upstream of the CFTR gene and the MUC1 gene

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12 December 2020

Enhancement of metastatic properties of pancreatic cancer cells by MUC1 gene encoding an anti-adhesion molecule

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12 December 2020

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

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12 December 2020

Cystic fibrosis mice lacking Muc1 have reduced amounts of intestinal mucus

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12 December 2020

The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail

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12 December 2020

The mouse episialin (Muc1) gene and its promoter: rapid evolution of the repetitive domain in the protein

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12 December 2020

MUC1 isoform specific monoclonal antibody 6E6/2 detects preferential expression of the novel MUC1/Y protein in breast and ovarian cancer

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12 December 2020

Modulation of Muc-1 mucin expression in the mouse uterus during the estrus cycle, early pregnancy and placentation

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12 December 2020

Identification of an HLA-A11-restricted epitope from the tandem repeat domain of the epithelial tumor antigen mucin

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12 December 2020

Expression of mucin 1 (MUC1) in esophageal squamous-cell carcinoma: its relationship with prognosis

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12 December 2020

Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis

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12 December 2020

MUC1 (episialin) expression in non-small cell lung cancer is independent of EGFR and c-erbB-2 expression and correlates with poor survival in node positive patients

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12 December 2020

Elevated soluble MUC1 levels and decreased anti-MUC1 antibody levels in patients with multiple myeloma

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12 December 2020

Purification of nuclear proteins that potentially regulate transcription of the MUC1 mucin gene induced by a soluble factor

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12 December 2020

Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin

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12 December 2020

Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene

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12 December 2020

The biological role of mucins in cellular interactions and immune regulation: prospects for cancer immunotherapy

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12 December 2020

MUC1/episialin: a critical barrier in the female reproductive tract

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12 December 2020

Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic, and colon cancer patients

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12 December 2020

The structure and assembly of secreted mucins

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12 December 2020

The immunogenicity of MUC1 peptides and fusion protein.

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12 December 2020

Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells

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12 December 2020

Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors

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12 December 2020

Definition of MHC-restricted CTL epitopes from non-variable number of tandem repeat sequence of MUC1.

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12 December 2020

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein

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12 December 2020

Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines

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12 December 2020

Cytotoxic T cells from ovarian malignant tumors can recognize polymorphic epithelial mucin core peptides

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12 December 2020

Delayed mammary tumor progression in Muc-1 null mice.

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12 December 2020

Multiple protein forms of the human breast tumor-associated epithelial membrane antigen (EMA) are generated by alternative splicing and induced by hormonal stimulation

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12 December 2020

The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer

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12 December 2020

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

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12 December 2020

Tissue-specific expression of a human polymorphic epithelial mucin (MUC1) in transgenic mice

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12 December 2020

Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients

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12 December 2020

Differential colon cancer cell adhesion to E-, P-, and L-selectin: role of mucin-type glycoproteins.

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12 December 2020

Mucins bearing the cancer-associated sialosyl-Tn antigen mediate inhibition of natural killer cell cytotoxicity

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12 December 2020

MUC1 expressed in PanC1 cells decreases adhesion to type 1 collagen but increases contraction in collagen lattices

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12 December 2020

Estrogen receptor does not directly regulate the murine Muc-1 promoter

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12 December 2020

A stat-responsive element in the promoter of the episialin/MUC1 gene is involved in its overexpression in carcinoma cells

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12 December 2020

Expression and steroid hormonal control of Muc-1 in the mouse uterus.

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12 December 2020

A MUC1 mucin secreted from a colon carcinoma cell line inhibits target cell lysis by natural killer cells

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12 December 2020

DF3 antigen, a human epithelial cell mucin, inhibits adhesion of eosinophils to antibody-coated targets

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12 December 2020

Analysis of mammalian MUC1 genes reveals potential functionally important domains

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12 December 2020

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

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12 December 2020

Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit

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12 December 2020

Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms.

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12 December 2020

ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner

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12 December 2020

Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z).

1 reference

12 December 2020

Purification and characterization of a membrane-bound and a secreted mucin-type glycoprotein carrying the carcinoma-associated sialyl-Lea epitope on distinct core proteins

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12 December 2020

The polymorphic epithelial mucin MUC1 in human endometrium is regulated with maximal expression in the implantation phase

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12 December 2020

Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin.

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12 December 2020

Increased invasiveness of MUC1 and cDNA-transfected human gastric cancer MKN74 cells

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12 December 2020

Serum markers casa, cea, cyfra-21-1, msa, nse, tpa and tps in lung-cancer

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12 December 2020

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

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12 December 2020

Cancer statistics, 2000.

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12 December 2020

Cloning of partial cDNA encoding differentiation and tumor-associated mucin glycoproteins expressed by human mammary epithelium

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12 December 2020

Bacterial conjunctivitis in Muc1 null mice

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12 December 2020

Rapid induction of primary human CD4+ and CD8+ T cell responses against cancer-associated MUC1 peptide epitopes

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12 December 2020

MUC1-specific immune responses in human MUC1 transgenic mice immunized with various human MUC1 vaccines

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12 December 2020

Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules.

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12 December 2020

Two GC boxes (Sp1 sites) are involved in regulation of the activity of the epithelium-specific MUC1 promoter.

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12 December 2020

Human B-cell immune response to the polymorphic epithelial mucin.

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12 December 2020

Antibodies to the cytoplasmic domain of the MUC1 mucin show conservation throughout mammals

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12 December 2020

MUC1 expression in hematopoietic tissues

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12 December 2020

Soluble MUC1 secreted by human epithelial cancer cells mediates immune suppression by blocking T-cell activation

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12 December 2020

MUC1 synthetic peptide inhibition of intercellular adhesion molecule-1 and MUC1 binding requires six tandem repeats.

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12 December 2020

Detection of a circulating antibody against a peptide epitope on a mucin core protein, MUC1, in ulcerative colitis

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12 December 2020

Expression of MUC1 on myeloma cells and induction of HLA-unrestricted CTL against MUC1 from a multiple myeloma patient

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12 December 2020

Analysis of the promoter of the MUC1 gene overexpressed in breast cancer

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12 December 2020

Unbranched polylactosamino-O-glycans on human skim milk mucins exhibit Gal beta(1-4)GlcNAc beta(1-6) repeating units

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12 December 2020

Expression of tumor-associated epitopes on Epstein-Barr virus-immortalized B-cells and Burkitt's lymphomas transfected with epithelial mucin complementary DNA.

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12 December 2020

Phosphorylation of the cytoplasmic domain of the MUC1 mucin correlates with changes in cell-cell adhesion

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12 December 2020

Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism

1 reference

12 December 2020

Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein

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12 December 2020

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

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12 December 2020

Expression of mucin carbohydrates and core proteins in carcinomas of the ampulla of Vater: their relationship to prognosis.

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12 December 2020

Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids

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12 December 2020

Mice with spontaneous pancreatic cancer naturally develop MUC-1-specific CTLs that eradicate tumors when adoptively transferred

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12 December 2020

Inhibition of adhesion of S-fimbriated Escherichia coli to buccal epithelial cells by human milk fat globule membrane components: a novel aspect of the protective function of mucins in the nonimmunoglobulin fraction

1 reference

12 December 2020

Vaccinia virus MUC1 immunization of mice: immune response and protection against the growth of murine tumors bearing the MUC1 antigen.

1 reference

12 December 2020

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women.

1 reference

12 December 2020

An enzyme-linked immunosorbent assay for the measurement of circulating antibodies to polymorphic epithelial mucin (MUC1)

1 reference

12 December 2020

Reactivity of natural and induced human antibodies to MUC1 mucin with MUC1 peptides and n-acetylgalactosamine (GalNAc) peptides

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12 December 2020

Why are proteins O-glycosylated?

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12 December 2020

Vaccination of high-risk breast cancer patients with mucin-1 (MUC1) keyhole limpet hemocyanin conjugate plus QS-21.

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12 December 2020

Augmenting the immunogenicity of synthetic MUC1 peptide vaccines in mice

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12 December 2020

Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccine

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12 December 2020

Factors effecting the measurement of tumor-associated MUC1 mucins in serum

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12 December 2020

Preferential expression of novel MUC1 tumor antigen isoforms in human epithelial tumors and their tumor-potentiating function

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12 December 2020

Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucins secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion.

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12 December 2020

Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide.

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12 December 2020

Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model

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12 December 2020

Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis

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12 December 2020

The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin

1 reference

12 December 2020

Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) in serum and ascites of patients with adenocarcinoma

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12 December 2020

Determination of apical membrane polarity in mammary epithelial cell cultures: The role of cell-cell, cell-substratum, and membrane-cytoskeleton interactions

1 reference

12 December 2020

Summary report on the ISOBM TD-4 Workshop: analysis of 56 monoclonal antibodies against the MUC1 mucin. San Diego, Calif., November 17-23, 1996.

1 reference

12 December 2020

Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone.

1 reference

12 December 2020

MUC1 dysregulation as the consequence of a t(1;14)(q21;q32) translocation in an extranodal lymphoma.

1 reference

12 December 2020

Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini.

1 reference

12 December 2020

A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma

1 reference

12 December 2020

Induction of humoral and cellular responses in cynomolgus monkeys immunised with mannan-human MUC1 conjugates.

1 reference

12 December 2020

Immunization of chimpanzees with tumor antigen MUC1 mucin tandem repeat peptide elicits both helper and cytotoxic T-cell responses.

1 reference

12 December 2020

Expression of genes coding for pS2, c-erbB2, estrogen receptor and the H23 breast tumor-associated antigen. A comparative analysis in breast cancer

1 reference

12 December 2020

Anti-MUC1 antibodies react directly with MUC1 peptides presented by class I H2 and HLA molecules.

1 reference

12 December 2020

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

1 reference

12 December 2020

Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells

1 reference

12 December 2020