(Q28216145)

1

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R Landgraf

2

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T Horan

3

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D Slamon

4

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D Eisenberg

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

23 November 2001

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published in

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volume

276

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page(s)

44266-74

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issue

47

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cites work

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

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Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

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Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.

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Dimerization of cell surface receptors in signal transduction

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Bivalence of EGF-like ligands drives the ErbB signaling network

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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Heregulin induces tyrosine phosphorylation of HER4/p180erbB4

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Association of signaling proteins with a nonmitogenic heterodimeric complex composed of epidermal growth factor receptor and kinase-inactive p185c-neu

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Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

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Signal transduction by receptors with tyrosine kinase activity

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Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

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Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3

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Growth factor receptor tyrosine kinases

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All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor

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Human epidermal growth factor receptor residue covalently cross-linked to epidermal growth factor

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Direct identification of residues of the epidermal growth factor receptor in close proximity to the amino terminus of bound epidermal growth factor

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Two EGF molecules contribute additively to stabilization of the EGFR dimer

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Proxy activation of protein ErbB2 by heterologous ligands implies a heterotetrameric mode of receptor tyrosine kinase interaction

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ErbB receptor activation, cell morphology changes, and apoptosis induced by anti-Her2 monoclonal antibodies

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Cytotoxicity and specificity of directed toxins composed of diphtheria toxin and the EGF-like domain of heregulin beta1.

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Amino acid analysis utilizing phenylisothiocyanate derivatives

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Amino acid substitution matrices from protein blocks

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The interpretation of protein structures: Estimation of static accessibility

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The CCP4 suite: programs for protein crystallography

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Heregulin reverses the oligomerization of HER3.

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Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptor

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Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor

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Mapping of an NH2-terminal ligand binding site of the insulin receptor by alanine scanning mutagenesis

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Replacements of leucine 87 in human insulin receptor alter affinity for insulin

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