(Q28216580)

English

Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

scientific article (publication date: 11 October 2002)

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scholarly article

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Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells (English)

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author name string

Jaejoon Won

1

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Jeongbin Yim

2

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Tae Kook Kim

3

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language of work or name

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publication date

11 October 2002

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Journal of Biological Chemistry

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277

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38230-8

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41

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Specific association of human telomerase activity with immortal cells and cancer

1 reference

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Aging and cancer: are telomeres and telomerase the connection?

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Replicative senescence and cell immortality: the role of telomeres and telomerase

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Telomere biology in human aging and aging syndromes

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Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

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21 January 2018

The RNA component of human telomerase

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A mammalian telomerase-associated protein

1 reference

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21 January 2018

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1 reference

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21 January 2018

In vivo and in vitro analyses of Myc for differential promoter activities of the human telomerase (hTERT) gene in normal and tumor cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Telomerase activity in hybrids between telomerase-negative and telomerase-positive immortal human cells is repressed in the different complementation groups but not in the same complementation group of immortality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Identification and characterization of negative regulatory elements of the human telomerase catalytic subunit (hTERT) gene promoter: possible role of MZF-2 in transcriptional repression of hTERT.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Identification of Mad as a repressor of the human telomerase (hTERT) gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Telomerase activation by histone deacetylase inhibitor in normal cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Histone deacetylase 1 can repress transcription by binding to Sp1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function

1 reference

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21 January 2018

Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Role of the LXCXE binding site in Rb function

1 reference

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21 January 2018

Insulin-like growth factor-I regulates transcription of the elastin gene through a putative retinoblastoma control element. A role for Sp3 acting as a repressor of elastin gene transcription.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Platelet-derived growth factor-stimulated expression of the MCP-1 immediate-early gene involves an inhibitory multiprotein complex

1 reference

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21 January 2018

Identification of SP3 as a negative regulatory transcription factor in the monocyte expression of growth hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Differential regulation of hepatitis B virus gene expression by the Sp1 transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Sp1 activates and inhibits transcription from separate elements in the proximal promoter of the human adenine nucleotide translocase 2 (ANT2) gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

A role for Sp and helix-loop-helix transcription factors in the regulation of the human Id4 gene promoter activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

An Sp1-binding silencer element is a critical negative regulator of the megakaryocyte-specific alphaIIb gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

On the role of the general transcription factor Sp1 in the activation and repression of diverse mammalian oxidative phosphorylation genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Sodium butyrate induces transcription from the G alpha(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Telomere end-replication problem and cell aging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Toward identifying a cellular determinant of telomerase repression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

The Wilms' tumor 1 tumor suppressor gene represses transcription of the human telomerase reverse transcriptase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206064200

21 January 2018

Identifiers

10.1074/JBC.M206064200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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