(Q28236769)

English

A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor

scientific article (publication date: April 1997)

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A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor (English)

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author name string

J F Gauchat

1

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E Schlagenhauf

2

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N P Feng

3

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R Moser

4

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M Yamage

5

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P Jeannin

6

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S Alouani

7

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G Elson

8

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L D Notarangelo

9

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T Wells

10

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H P Eugster

11

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J Y Bonnefoy

12

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language of work or name

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publication date

April 1997

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European Journal of Immunology

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27

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4

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971-8

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Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

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Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction

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Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures

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IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2

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Membranes of activated CD4+ T cells expressing T cell receptor (TcR) alpha beta or TcR gamma delta induce IgE synthesis by human B cells in the presence of interleukin-4

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Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

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TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

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Mitogen plus interleukin 4 induction of C epsilon transcripts in B lymphoid cells

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Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production

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VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.

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The role of eosinophils in the pathogenesis of asthma

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Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.

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Role of IRS-2 in insulin and cytokine signalling

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Interleukin-13 signal transduction in lymphohemopoietic cells. Similarities and differences in signal transduction with interleukin-4 and insulin

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Similarities and differences in signal transduction by interleukin 4 and interleukin 13: analysis of Janus kinase activation

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Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4

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An interleukin-4-induced transcription factor: IL-4 Stat

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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

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Essential role of Stat6 in IL-4 signalling

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

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The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor

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IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells

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Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.

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IL-4 and IL-13 receptors: are they one and the same?

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Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

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Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain

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10.1002/EJI.1830270425

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24 November 2022

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