(Q28239090)

English

Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia

scientific article (publication date: April 2005)

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scholarly article

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Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia (English)

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author name string

Tatiana Lipina

1

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Viviane Labrie

2

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Ina Weiner

3

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John Roder

4

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language of work or name

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publication date

April 2005

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Psychopharmacology

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179

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1

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54-67

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https://scigraph.springernature.com/pub.10.1007/s00213-005-2210-x

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Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging.

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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The DBA/2J strain and prepulse inhibition of startle: a model system to test antipsychotics?

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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The Effects of dizocilpine and phencyclidine on prepulse inhibition of the acoustic startle reflex and on prepulse-elicited reactivity in C57BL6 mice

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glutamate receptor genes: susceptibility factors in schizophrenia and depressive disorders?

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glutamate receptors and transporters in the hippocampus in schizophrenia.

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Imaging the PCP site of the NMDA ion channel

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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The "two-headed" latent inhibition model of schizophrenia: modeling positive and negative symptoms and their treatment

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Antagonism of phencyclidine-induced hyperactivity by glycine in mice.

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat.

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glycine regulation of the N-methyl-D-aspartate receptor-gated ion channel in hippocampal membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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The pharmacology of latent inhibition as an animal model of schizophrenia

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Clinical features of latent inhibition in schizophrenia

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Neural substrates of latent inhibition: the switching model

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Haloperidol- and clozapine-induced enhancement of latent inhibition with extended conditioning: implications for the mechanism of action of neuroleptic drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal-lesioned rats: reversal by glycine and a glycine transporter inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of phencyclidine (PCP) and (+)MK-801 on sensorimotor gating in CD-1 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Sensorimotor gating and schizophrenia. Human and animal model studies

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https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Drug-induced potentiation of prepulse inhibition of acoustic startle reflex in mice: a model for detecting antipsychotic activity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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The latent inhibition model of schizophrenia: further validation using the atypical neuroleptic, clozapine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Converging Evidence of NMDA Receptor Hypofunction in the Pathophysiology of Schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Clozapine and haloperidol modulate N-methyl-D-aspartate- and non-N-methyl-D-aspartate receptor-mediated neurotransmission in rat prefrontal cortical neurons in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption and potentiation of latent inhibition by risperidone: the latent inhibition model of atypical antipsychotic action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioral model of clinical drug action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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The delayed effects of DTG and MK-801 on latent inhibition in a conditioned taste-aversion paradigm.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Lamotrigine prevents ketamine but not amphetamine-induced deficits in prepulse inhibition in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glycine and D-serine decrease MK-801-induced hyperactivity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glutamatergic neurotransmission modulation and the mechanisms of antipsychotic atypicality

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Stereoselective antagonism by enantiomers of alanine and serine of phencyclidine-induced hyperactivity, stereotypy and ataxia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Glutamate and glycine decrease the affinity of [3H]MK-801 binding in the presence of Mg2+.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Effects of antipsychotic drugs on serotonin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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AMPA Receptor Trafficking at Excitatory Synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Comparative effects of glycine and D-cycloserine on persistent negative symptoms in schizophrenia: a retrospective analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered cortical glutamate neurotransmission in schizophrenia: evidence from morphological studies of pyramidal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The switching model of latent inhibition: an update of neural substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine blunts N-methyl-D-aspartate antagonist-induced psychosis: a study with ketamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of serotonin 2A receptors in phencyclidine-induced disruption of prepulse inhibition of the acoustic startle in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the phencyclidine model of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The latent inhibition model dissociates between clozapine, haloperidol, and ritanserin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phencyclidine does not disrupt latent inhibition in rats: implications for animal models of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: a critical review

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor blockade and hippocampal neuronal loss impair fear conditioning and position habit reversal in C57Bl/6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Effects of nicotine and amphetamine on latent inhibition in human subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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A.E. Bennett Research Award. Reversal of phencyclidine-induced effects by glycine and glycine transport inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

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Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine therapy of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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The emerging role of glutamate in the pathophysiology and treatment of schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Disruption of latent inhibition by acute administration of low doses of amphetamine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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A behavioural pattern analysis of hypoglutamatergic mice--effects of four different antipsychotic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic administration of MK-801 produces an abnormally persistent latent inhibition which is reversed by clozapine but not haloperidol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine modulators in schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of dizocilpine-induced disruption of prepulse inhibition of an acoustic startle response by the 5-HT2 receptor antagonist ketanserin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NMDA-receptor antagonist MK-801 selectively disrupts reversal learning in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic influences on latent inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

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Seroquel, clozapine and chlorpromazine restore sensorimotor gating in ketamine-treated rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relation between latent inhibition and symptom-types in young schizophrenics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15759151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00213-005-2210-X

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