(Q28239230)

English

Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region

scientific article (publication date: 2007)

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scholarly article

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Measurement of serotonin 5-HT1A receptor binding using positron emission tomography and [carbonyl-(11)C]WAY-100635-considerations on the validity of cerebellum as a reference region (English)

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positron emission tomography

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based on heuristic

inferred from title

author name string

Jussi Hirvonen

1

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Jaana Kajander

2

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Topias Allonen

3

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Vesa Oikonen

4

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Kjell Någren

5

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Jarmo Hietala

6

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language of work or name

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publication date

January 2007

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Journal of Cerebral Blood Flow & Metabolism

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27

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1

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185-95

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describes a project that uses

positron emission tomography

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based on heuristic

inferred from title

Statistical parametric maps in functional imaging: A general linear approach

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Persistent reduction in brain serotonin1A receptor binding in recovered depressed men measured by positron emission tomography with [11C]WAY-100635.

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Transient localization of 5-HT1A receptors in human cerebellum during development.

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Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET.

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Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.

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Regional heterogeneity of 5-HT1A receptors in human cerebellum as assessed by positron emission tomography

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Validation and reproducibility of measurement of 5-HT1A receptor parameters with [carbonyl-11C]WAY-100635 in humans: comparison of arterial and reference tisssue input functions.

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Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors

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Evidence of increased serotonin-1A receptor binding in type 2 diabetes: a positron emission tomography study

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A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables

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Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy

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Abnormal persistence of cerebellar serotonin-1A receptors in schizophrenia suggests failure to regress in neonates

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Models and methods for derivation of in vivo neuroreceptor parameters with PET and SPECT reversible radiotracers

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Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635.

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Serotonin 5-HT1A receptor binding potential declines with age as measured by [11C]WAY-100635 and PET.

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Brain serotonin 1A receptor binding in bulimia nervosa

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[11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS.

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A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

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Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635

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10.1038/SJ.JCBFM.9600326

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