(Q28250177)

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The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression

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scholarly article

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Jun Ming Wang

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Patrick B Johnston

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Bret Gene Ball

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Roberta Diaz Brinton

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

0 references

publication date

1 May 2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

25

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

4706-4718

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Neurosteroidogenesis in astrocytes, oligodendrocytes, and neurons of cerebral cortex of rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid metabolism and effects in central and peripheral glial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium dynamics of neocortical ventricular zone cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis and the cell cycle: with this RING I do thee destroy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidences of early neurosteroid synthesis in the developing rat central nervous system and placenta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopregnanolone and dehydroepiandrosterone response to corticotropin-releasing factor in patients suffering from Alzheimer's disease and vascular dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Visualization of neurogenesis in the central nervous system using nestin promoter-GFP transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum allopregnanolone levels in pregnant women: changes during pregnancy, at delivery, and in hypertensive patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle kinetics and immunohistochemical characterization of dissociated fetal neocortical cultures: evidence that differentiated neurons have mitotic capacity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal differentiation and morphological integration of hippocampal progenitor cells transplanted to the retina of immature and mature dystrophic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ganaxolone for treating intractable infantile spasms: a multicenter, open-label, add-on trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nestin-EGFP transgenic mice: visualization of the self-renewal and multipotency of CNS stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids: beginning of the story

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone and the oligodendroglial lineage: stage-dependent biosynthesis and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids: biochemistry and clinical significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional neurogenesis in the adult hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astroglia induce neurogenesis from adult neural stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrphostins protect neuronal cells from oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopregnanolone activates GABA(A) receptor/Cl(-) channels in a multiphasic manner in embryonic rat hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal differentiation of stem cells isolated from adult muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of energy restriction: effects of corticosterone on cell growth, cell cycle machinery, and apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous activity-independent intracellular calcium signals in the developing spinal cord of the zebrafish embryo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, regulation, and function of neurosteroids

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory actions of GABA in developing brain are mediated by l-type Ca2+ channels and dependent on age, sex, and brain region

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of cell survival and proliferation of postnatal PSA-NCAM(+) progenitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopregnanolone serum levels and expression of 5α-reductase and 3α-hydroxysteroid dehydrogenase isoforms in hippocampal and temporal cortex of patients with epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creating new neurons in old brains

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High Efficacy of Clonal Growth and Expansion of Adult Neural Stem Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The luteinizing hormone surge is preceded by an estrogen-induced increase of hypothalamic progesterone in ovariectomized and adrenalectomized rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of a GABAA receptor coupled steroid recognition site

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developing neurons make the switch

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Using human neural stem cells to model neurological disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurogenesis in the adult brain: new strategies for central nervous system diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitation-neurogenesis coupling in adult neural stem/progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interneurons set the tune of developing networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of allopregnanolone on cerebellar granule cells neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3alpha,5alpha-Tetrahydroprogesterone (allopregnanolone) and gamma-aminobutyric acid: autocrine/paracrine interactions in the control of neonatal PSA-NCAM+ progenitor proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA mediated excitation in immature rat CA3 hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids: a new brain function?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonneuronal localization for steroid converting enzyme: 3 alpha-hydroxysteroid oxidoreductase in olfactory tubercle of rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA-dependent modulation of the Cl- ionophore by steroids in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle dependence of foamy retrovirus infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced survival and neuronal differentiation of adrenal chromaffin cells cografted into the striatum with NGF-producing fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transient three-plasmid expression system for the production of high titer retroviral vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one induces cytoarchitectural regression in cultured fetal hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of neuron-specific tubulin defines a novel population in the proliferative layers of the developing telencephalon

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of murine leukemia virus DNA depends on mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A putative receptor for neurosteroids on the GABAA receptor complex: the pharmacological properties and therapeutic potential of epalons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rise in intracellular calcium via a nongenomic effect of allopregnanolone in fetal rat hypothalamic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a subdomain in the Moloney murine leukemia virus envelope protein involved in receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid metabolizing enzymes in pluripotential progenitor central nervous system cells: effect of differentiation and maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The division of neuronal progenitor cells during migration in the neonatal mammalian forebrain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ontogeny of 5 alpha-reductase (type 1) messenger ribonucleic acid expression in rat brain: early presence in germinal zones

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adult rat hippocampus contains primordial neural stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids: of the nervous system, by the nervous system, for the nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging is associated with changes in allopregnanolone concentrations in brain, endocrine glands and serum in male rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A measure of the mitotic index: studies of the abundance and half-life of p34cdc2 in cultured cells and normal and neoplastic tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of intracellular calcium fluctuation in precursor cells of the neocortical ventricular zone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The microglia/macrophage response in the neonatal rat facial nucleus following axotomy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15888646

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4520-04.2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15888646%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

ResearchGate publication ID

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