(Q28257171)

2

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L Haataja

3

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N Heisterkamp

4

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J Groffen

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

19 December 1997

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published in

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volume

272

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page(s)

32649-55

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issue

51

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cites work

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An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

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p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene

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Crkl is complexed with tyrosine-phosphorylated Cbl in Ph-positive leukemia

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CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

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p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

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Two species of human CRK cDNA encode proteins with distinct biological activities

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The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

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Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins

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Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts

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Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

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Adhesion through the interaction of lymphocyte function-associated antigen-1 with intracellular adhesion molecule-1 induces tyrosine phosphorylation of p130cas and its association with c-CrkII.

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Paxillin: a cytoskeletal target for tyrosine kinases

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p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

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Bcr/Abl expression stimulates integrin function in hematopoietic cell lines

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Integrin-mediated regulation of hematopoiesis: do BCR/ABL-induced defects in integrin function underlie the abnormal circulation and proliferation of CML progenitors?

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Isolation and sequence analysis of a novel human tyrosine kinase gene

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae

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Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

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DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

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Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells

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Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein

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Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

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SH2 domains recognize specific phosphopeptide sequences

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A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

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Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

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Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins

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Altered adhesive interactions with marrow stroma of haematopoietic progenitor cells in chronic myeloid leukaemia

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