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Dopamine D3 receptor antagonists as therapeutic agents
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Europe PubMed Central
title
Dopamine D3 receptor antagonists as therapeutic agents
(English)
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main subject
dopamine
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author name string
Jeffrey N Joyce
series ordinal
1
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Mark J Millan
series ordinal
2
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language of work or name
English
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publication date
1 July 2005
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published in
Drug Discovery Today
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volume
10
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issue
13
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page(s)
917-25
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cites work
Dopamine receptor signaling
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Crossref
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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inferred from DOI database lookup
Human dopamine D(3) receptors mediate mitogen-activated protein kinase activation via a phosphatidylinositol 3-kinase and an atypical protein kinase C-dependent mechanism
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7 January 2021
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Dopamine D3 receptor as a therapeutic target for antipsychotic and antiparkinsonian drugs
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole
1 reference
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7 January 2021
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Adenosine A2A receptor and dopamine D3 receptor interactions: evidence of functional A2A/D3 heteromeric complexes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Distribution of dopamine D3 receptor expressing neurons in the human forebrain: comparison with D2 receptor expressing neurons
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Possible implications of the dopamine D(3) receptor in schizophrenia and in antipsychotic drug actions
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Dopamine D3 receptors expressed by all mesencephalic dopamine neurons
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Rat striatal and mesencephalic neurons contain the long isoform of the D2 dopamine receptor mRNA.
1 reference
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7 January 2021
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D(3) receptor ligands modulate extracellular dopamine clearance in the nucleus accumbens
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7 January 2021
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Lack of functional D2 receptors prevents the effects of the D3-preferring agonist (+)-PD 128907 on dialysate dopamine levels
1 reference
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7 January 2021
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Phenotypic analysis of dopamine receptor knockout mice; recent insights into the functional specificity of dopamine receptor subtypes
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7 January 2021
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Dopamine D3 receptor agonists produce similar decreases in body temperature and locomotor activity in D3 knock-out and wild-type mice
1 reference
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Crossref
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7 January 2021
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Behavioral effects of dopamine agonists and antagonists in MPTP-lesioned D3 receptor knockout mice
1 reference
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reference URL
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7 January 2021
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Recent advances in the development of dopamine D(3) receptor agonists and antagonists
1 reference
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7 January 2021
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Progress in developing D3 dopamine receptor ligands as potential therapeutic agents for neurological and neuropsychiatric disorders
1 reference
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7 January 2021
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The role of dopamine D3 compared with D2 receptors in the control of locomotor activity: a combined behavioural and neurochemical analysis with novel, selective antagonists in rats
1 reference
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7 January 2021
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inferred from DOI database lookup
Effects of dopamine D3 receptor antagonists on spontaneous and agonist-reduced motor activity in NMRI mice and Wistar rats: comparative study with nafadotride, U 99194A and SB 277011.
1 reference
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Crossref
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7 January 2021
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Comparative pharmacology of human dopamine D(2)-like receptor stable cell lines coupled to calcium flux through Galpha(qo5).
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Evidence for regulation of body temperature in rats by dopamine D2 receptor and possible influence of D1 but not D3 and D4 receptors
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
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Effect of the D3 dopamine receptor partial agonist BP897 [N-[4-(4-(2-methoxyphenyl)piperazinyl)butyl]-2-naphthamide] on L-3,4-dihydroxyphenylalanine-induced dyskinesias and parkinsonism in squirrel monkeys.
1 reference
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7 January 2021
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The dopamine D3 receptor partial agonist, BP 897, is an antagonist at human dopamine D3 receptors and at rat somatodendritic dopamine D3 receptors
1 reference
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Crossref
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7 January 2021
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Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence
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Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonist
1 reference
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7 January 2021
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N-methyl-D-aspartate receptor-coupled glycineB receptors in the pathogenesis and treatment of schizophrenia: a critical review
1 reference
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Influence of dopamine on limbic inputs to the nucleus accumbens
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7 January 2021
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Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia. A postmortem study.
1 reference
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7 January 2021
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D2 but not D3 receptors are elevated after 9 or 11 months chronic haloperidol treatment: influence of withdrawal period
1 reference
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7 January 2021
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Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies
1 reference
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7 January 2021
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Half a century of antipsychotics and still a central role for dopamine D2 receptors
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7 January 2021
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Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa
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7 January 2021
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Increased rewarding properties of morphine in dopamine-transporter knockout mice
1 reference
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7 January 2021
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Methamphetamine-induced loss of striatal dopamine innervation in BDNF heterozygote mice does not further reduce D3 receptor concentrations
1 reference
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7 January 2021
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BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization
1 reference
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7 January 2021
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Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment
1 reference
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7 January 2021
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Meta-analysis of DRD3 gene and schizophrenia: ethnic heterogeneity and significant association in Caucasians.
1 reference
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7 January 2021
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Dopamine D3 receptor gene Ser9Gly variant and schizophrenia: association study and meta-analysis
1 reference
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7 January 2021
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Dopamine D3 receptor gene not associated with symptomatology of major psychoses
1 reference
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Crossref
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7 January 2021
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Pharmacogenetics of dopamine receptors and response to antipsychotic drugs in schizophrenia--an update
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7 January 2021
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inferred from DOI database lookup
Association between dopamine D3 receptor gene polymorphisms and schizophrenia in an isolate population
1 reference
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7 January 2021
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Pharmacogenetics of treatment in first-episode schizophrenia: D3 and 5-HT2C receptor polymorphisms separately associate with positive and negative symptom response
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective blockade of D(3) dopamine receptors enhances the anti-parkinsonian properties of ropinirole and levodopa in the MPTP-lesioned primate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
retrieved
7 January 2021
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The positive and negative syndrome scale (PANSS) for schizophrenia
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Role of the dopamine D3 receptor in reactivity to cocaine-associated cues in mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Double activity imaging reveals distinct cellular targets of haloperidol, clozapine and dopamine D(3) receptor selective RGH-1756.
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Clozapine-, but not haloperidol-, induced increases in deltaFosB-like immunoreactivity are completely blocked in the striatum of mice lacking D3 dopamine receptors.
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Atypical, but not typical, antipsychotic drugs increase cortical acetylcholine release without an effect in the nucleus accumbens or striatum
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Memory-related acetylcholine efflux from rat prefrontal cortex and hippocampus: a microdialysis study
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Hypofrontality in schizophrenia: a meta-analysis of functional imaging studies
1 reference
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7 January 2021
based on heuristic
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Relationship of behavioural and symptomatic syndromes in schizophrenia to spatial working memory and attentional set-shifting ability.
1 reference
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reference URL
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7 January 2021
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Antipsychotic drugs: evolving mechanisms of action with improved therapeutic benefits
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Selective antagonism at dopamine D3 receptors enhances monoaminergic and cholinergic neurotransmission in the rat anterior cingulate cortex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Dopamine D3 receptor antagonists improve the learning performance in memory-impaired rats
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Mice lacking dopamine D2 and D3 receptors exhibit differential activation of prefrontal cortical neurons during tasks requiring attention
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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D1 agonist dihydrexidine releases acetylcholine and improves cognitive performance in rats.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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On the trail of a cognitive enhancer for the treatment of schizophrenia
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of dopamine receptor antagonists on hyperlocomotion induced by cocaine, amphetamine, MK-801 and the dopamine D1 agonist C-APB in mice
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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The dopamine D3 receptor mediates locomotor hyperactivity induced by NMDA receptor blockade
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Prepulse inhibition of the acoustically evoked startle reflex in patients with an acute schizophrenic psychosis--a longitudinal study.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice
1 reference
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https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist
1 reference
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reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
D3 dopamine receptor, behavioral sensitization, and psychosis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Does dopamine sensitization underlie the association between schizophrenia and drug abuse?
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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Acute administration of the selective D3 receptor antagonist SB-277011A blocks the acquisition and expression of the conditioned place preference response to heroin in male rats
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
based on heuristic
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The D3R partial agonist, BP 897, attenuates the discriminative stimulus effects of cocaine and D-amphetamine and is not self-administered
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1359-6446%2805%2903491-4
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7 January 2021
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Identifiers
DOI
10.1016/S1359-6446(05)03491-4
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3129477
OpenCitations bibliographic resource ID
3129477
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3129477
PubMed ID
15993811
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3129477
ResearchGate publication ID
7749985
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