(Q28261344)

2

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Mario Patrizio

3

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Laura Franchini

4

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Maria Antonietta Ajmone-Cat

5

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Giulio Levi

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

6

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language of work or name

English

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publication date

May 2004

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published in

Neurochemical Research

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volume

29

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page(s)

965-78

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issue

5

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cites work

1 reference

12 December 2020

Properties of voltage-gated potassium currents of microglia differentiated with granulocyte/macrophage colony-stimulating factor

1 reference

12 December 2020

Methamphetamine potentiates HIV-1 Tat protein-mediated activation of redox-sensitive pathways in discrete regions of the brain

1 reference

12 December 2020

The isoprostanes: unique bioactive products of lipid peroxidation

1 reference

12 December 2020

Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions

1 reference

12 December 2020

Propentofylline inhibits production of TNFalpha and infection of LP-BM5 murine leukemia virus in glial cells

1 reference

12 December 2020

Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1

1 reference

12 December 2020

Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease

1 reference

12 December 2020

Tat protein of human immunodeficiency virus type 1 represses expression of manganese superoxide dismutase in HeLa cells

1 reference

12 December 2020

Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement

1 reference

12 December 2020

Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia

1 reference

12 December 2020

Impaired production of cytokines is an independent predictor of mortality in HIV-1-infected patients

1 reference

12 December 2020

The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures

1 reference

12 December 2020

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

1 reference

12 December 2020

Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo

1 reference

12 December 2020

Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide

1 reference

12 December 2020

Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production

1 reference

12 December 2020

Neuronal injury associated with HIV-1: approaches to treatment

1 reference

12 December 2020

Isoprostanes, novel markers of oxidative injury, help understanding the pathogenesis of neurodegenerative diseases.

1 reference

12 December 2020

Pivotal role of cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4+ T cell hyperactivation and HIV type 1 replication

1 reference

12 December 2020

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence

1 reference

12 December 2020

Immunopathogenic mechanisms of HIV infection: cytokine induction of HIV expression

1 reference

12 December 2020

Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat.

1 reference

12 December 2020

Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity

1 reference

12 December 2020

Expression of excitatory amino acid transporter-1 in brain macrophages and microglia of HIV-infected patients. A neuroprotective role for activated microglia?

1 reference

12 December 2020

Molecular mechanisms involved in the regulation of amino acid transport

1 reference

12 December 2020

Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor

1 reference

12 December 2020

1 reference

12 December 2020

Role of HIV-1 Tat and CC chemokine MIP-1alpha in the pathogenesis of HIV associated central nervous system disorders

1 reference

12 December 2020

The role of tumour necrosis factor, interleukin 6, interferon-gamma and inducible nitric oxide synthase in the development and pathology of the nervous system.

1 reference

12 December 2020

Upregulation of Kv1.3 K(+) channels in microglia deactivated by TGF-beta

1 reference

12 December 2020

Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors

1 reference

12 December 2020

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation

1 reference

12 December 2020

Novel mechanism and factor for regulation by HIV-1 Tat

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12 December 2020

Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide

1 reference

12 December 2020

Neuroprotective effects of prostaglandin E2 or cAMP against microglial and neuronal free radical mediated toxicity associated with inflammation

1 reference

12 December 2020

Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

1 reference

12 December 2020

Cultured microglial cells have a distinct pattern of membrane channels different from peritoneal macrophages

1 reference

12 December 2020

HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.

1 reference

12 December 2020

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha

1 reference

12 December 2020

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

1 reference

12 December 2020

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat

1 reference

12 December 2020

HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state

1 reference

12 December 2020

Analysis of B7-1 and B7-2 costimulatory ligands in cultured mouse microglia: upregulation by interferon-gamma and lipopolysaccharide and downregulation by interleukin-10, prostaglandin E2 and cyclic AMP-elevating agents.

1 reference

12 December 2020

Vasoactive intestinal peptide and pituitary adenylyl cyclase-activating polypeptide inhibit tumor necrosis factor-alpha production in injured spinal cord and in activated microglia via a cAMP-dependent pathway

1 reference

12 December 2020

Beta-chemokines and human immunodeficiency virus type-1 proteins evoke intracellular calcium increases in human microglia

1 reference

12 December 2020

Autoantibodies to TNFalpha in HIV-1 infection: prospects for anti-cytokine vaccine therapy

1 reference

12 December 2020

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

1 reference

12 December 2020

Activation of human immunodeficiency virus

1 reference

12 December 2020

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice

1 reference

12 December 2020

Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: comparison with other types of cAMP-elevating agents

1 reference

12 December 2020

A Kv1.5 to Kv1.3 switch in endogenous hippocampal microglia and a role in proliferation

1 reference

12 December 2020

beta-adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia.

1 reference

12 December 2020

NFkappaB activation, TNF-alpha expression, and apoptosis in the AIDS-Dementia-Complex.

1 reference

12 December 2020

Altered outward-rectifying K(+) current reveals microglial activation induced by HIV-1 Tat protein.

1 reference

12 December 2020

K+ channels and the microglial respiratory burst

1 reference

12 December 2020

Type 1/Type 2 immunity in infectious diseases

1 reference

12 December 2020

IL-12 production by central nervous system microglia is inhibited by astrocytes.

1 reference

12 December 2020

Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteins

1 reference

12 December 2020

Protein kinase C involvement in the resting and interferon-gamma-induced K+ channel profile of microglial cells

1 reference

12 December 2020

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

1 reference

12 December 2020

Potassium-inhibited processing of IL-1 beta in human monocytes

1 reference

12 December 2020

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

1 reference

12 December 2020

Oxidative stress, cell cycle, and neurodegeneration

1 reference

12 December 2020

Interferon-gamma and lipopolysaccharide reduce cAMP responses in cultured glial cells: reversal by a type IV phosphodiesterase inhibitor

1 reference

12 December 2020

Nitric oxide in autoimmune disease: cytotoxic or regulatory mediator?

1 reference

12 December 2020

Ion channels in rat microglia and their different sensitivity to lipopolysaccharide and interferon-gamma

1 reference

12 December 2020

Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

1 reference

12 December 2020

Human immunodeficiency virus type 1 genome activation induced by human T-cell leukemia virus type 1 Tax protein is through cooperation of NF-kappaB and Tat.

1 reference

12 December 2020

The HIV-1 Tat nuclear localization sequence confers novel nuclear import properties

1 reference

12 December 2020

Synergistic neurotoxicity of opioids and human immunodeficiency virus-1 Tat protein in striatal neurons in vitro

1 reference

12 December 2020

A soluble factor produced by macrophages mediates the neurotoxic effects of HIV-1 Tat in vitro

1 reference

12 December 2020

Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein.

1 reference

12 December 2020

Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon.

1 reference

12 December 2020

The promoter of the gene encoding 3',5'-cyclic adenosine monophosphate (cAMP) response element binding protein contains cAMP response elements: evidence for positive autoregulation of gene transcription

1 reference

12 December 2020

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes

1 reference

12 December 2020

Endocytosis and targeting of exogenous HIV-1 Tat protein

1 reference

12 December 2020

Differential regulation of cytokine-induced major histocompatibility complex class II expression and nitric oxide release in rat microglia and astrocytes by effectors of tyrosine kinase, protein kinase C, and cAMP

1 reference

12 December 2020

Interferon-gamma and nitric oxide down-regulate lipopolysaccharide-induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression

1 reference

12 December 2020

Potassium and calcium channels in lymphocytes

1 reference

12 December 2020

Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells.

1 reference

12 December 2020

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

1 reference

12 December 2020

Regulation of TNFalpha and TGFbeta-1 gene transcription by HIV-1 Tat in CNS cells.

1 reference

12 December 2020

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia

1 reference

12 December 2020

Neuronal injury in hippocampus with human immunodeficiency virus transactivating protein, Tat.

1 reference

12 December 2020

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

1 reference

12 December 2020

From the outside in: extracellular activities of HIV Tat.

1 reference

12 December 2020

Electrophysiological behavior of microglia

1 reference

12 December 2020

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

1 reference

12 December 2020

Isoprostanes as a biomarker of lipid peroxidation in humans: physiology, pharmacology and clinical implications

1 reference

12 December 2020

Ibudilast suppresses TNFalpha production by glial cells functioning mainly as type III phosphodiesterase inhibitor in the CNS.

1 reference

12 December 2020

HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium

1 reference

12 December 2020

Human immunodeficiency virus type 1 Tat protein stimulates inducible nitric oxide synthase expression and nitric oxide production in microglial cultures

1 reference

12 December 2020

Neurotoxicity of HIV-1 proteins gp120 and Tat in the rat striatum

1 reference

12 December 2020

Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages

1 reference

12 December 2020

Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain

1 reference

12 December 2020

Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms

1 reference

12 December 2020

Evidence for voltage modulation of IL-2 production in mitogen-stimulated human peripheral blood lymphocytes

1 reference

12 December 2020

Activation of human microglial cells by HIV-1 gp41 and Tat proteins

1 reference

12 December 2020

Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.

1 reference

12 December 2020

Pro-inflammatory and pro-oxidant properties of the HIV protein Tat in a microglial cell line: attenuation by 17 beta-estradiol

1 reference

12 December 2020

Regulation of Cellular Gene Expression and Function by the Human Immunodeficiency Virus Type 1 Tat Protein

1 reference

12 December 2020

Redox regulation of nuclear factor kappa B: therapeutic potential for attenuating inflammatory responses.

1 reference

12 December 2020

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

1 reference

12 December 2020

Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures

1 reference

12 December 2020

Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism

1 reference

12 December 2020

The human immunodeficiency virus type 1 regulatory protein Tat inhibits interferon-induced iNos activity in a murine macrophage cell line

1 reference

12 December 2020

Inflammatory stimuli induce a new K+ outward current in cultured rat microglia

1 reference

12 December 2020

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor

1 reference

12 December 2020

Neuropathologies in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1 Tat Protein under the Regulation of the Astrocyte-Specific Glial Fibrillary Acidic Protein Promoter and Doxycycline

1 reference

12 December 2020

Rolipram, a cyclic AMP-selective phosphodiesterase inhibitor, reduces neuronal damage following cerebral ischemia in the gerbil

1 reference

12 December 2020

Opposite effects of interferon-gamma and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities.

1 reference

12 December 2020

A CNS-enriched factor that binds to NF-kappa B and is required for interaction with HIV-1 tat

1 reference

12 December 2020

Glucocorticoid exacerbation of gp120 neurotoxicity: role of microglia

1 reference

12 December 2020

Electrophysiological properties of microglial cells in normal and pathologic rat brain slices.

1 reference

12 December 2020

Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes

1 reference

12 December 2020

Cellular uptake of the tat protein from human immunodeficiency virus

1 reference

12 December 2020

Human immunodeficiency virus type-1 Tat protein induces nuclear factor (NF)-kappaB activation and oxidative stress in microglial cultures by independent mechanisms.

1 reference

12 December 2020

Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR

1 reference

12 December 2020

Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Properties of K+ and Cl- channels and their involvement in proliferation of rat microglial cells

1 reference

12 December 2020

HIV-1 Tat protein mimicry of chemokines

1 reference

12 December 2020

Activation of nuclear factor kB in brains from children with HIV-I encephalitis

1 reference

12 December 2020

Downregulation of in vitro neurotoxicity of brain macrophages by prostaglandin E2 and a β-adrenergic agonist

1 reference

12 December 2020

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway

1 reference

12 December 2020

Voltage-gated currents expressed by rat microglia in culture

1 reference

12 December 2020

Role of calcium in tumor necrosis factor-alpha production by activated macrophages

1 reference

12 December 2020

10.1023/B:NERE.0000021241.90133.89

Identifiers

DOI

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Dimensions Publication ID

1036600620

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Fatcat ID

release_64owifygsfemnoerwkruuogbrm

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/64owifygsfemnoerwkruuogbrm

24 November 2022