(Q28262851)

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Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract

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Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract (English)

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author name string

Amar A Patil

1

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Yibin Cai

2

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Yongming Sang

3

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Frank Blecha

4

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Guolong Zhang

5

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language of work or name

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publication date

21 September 2005

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Physiological Genomics

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23

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1

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5-17

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Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Effects of positively selected sequence variations in human and Macaca fascicularis beta-defensins 2 on antimicrobial activity.

1 reference

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21 January 2018

Differential expression and antibacterial activity of epididymis protein 2 isoforms in the male reproductive tract of human and rhesus monkey (Macaca mulatta)

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

GeneWise and Genomewise

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Prediction of complete gene structures in human genomic DNA

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

1 reference

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21 January 2018

Beta-defensins and LL-37 in bronchoalveolar lavage fluid of patients with cystic fibrosis

1 reference

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21 January 2018

Expression of antimicrobial defensins in the male reproductive tract of rats, mice, and humans.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Primate beta-defensins--structure, function and evolution

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

EP2 splicing variants in rhesus monkey (Macaca mulatta) epididymis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Organization of the human gene encoding the epididymis-specific EP2 protein variants and its relationship to defensin genes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Arthropod and mollusk defensins--evolution by exon-shuffling

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Defensins: antimicrobial peptides of innate immunity

1 reference

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21 January 2018

Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Antimicrobial protection of the mouse testis: synthesis of defensins of the cryptdin family

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

The structure of human beta-defensin-2 shows evidence of higher order oligomerization

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Evolutionary diversification of the mammalian defensins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

BLAT—The BLAST-Like Alignment Tool

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Innate immune defences in the human endometrium

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

A molecular timescale for vertebrate evolution

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Primate defensins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

An antimicrobial peptide gene found in the male reproductive system of rats.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

The human cationic antimicrobial protein (hCAP-18) is expressed in the epithelium of human epididymis, is present in seminal plasma at high concentrations, and is attached to spermatozoa

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Signal sequence conservation and mature peptide divergence within subgroups of the murine beta-defensin gene family

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Evolution of primate theta-defensins: a serpentine path to a sweet tooth

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Solution structure of crotamine, a Na+ channel affecting toxin from Crotalus durissus terrificus venom

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Defensin-mediated innate immunity in the small intestine

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Identification, characterization, and evolution of a primate beta-defensin gene cluster

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Cloning and characterization of a novel sperm-associated isoantigen (E-3) with defensin- and lectin-like motifs expressed in rat epididymis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Molecular cloning and characterization of three beta-defensins from canine testes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

[beta]-defensins in lung host defense

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Discovery of five conserved beta -defensin gene clusters using a computational search strategy

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Duplication and selection in the evolution of primate beta-defensin genes

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Expression and activity of beta-defensins and LL-37 in the developing human lung

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Detection of human defensin 5 in reproductive tissues

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Plant defensins.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Macaque sperm release ESP13.2 and PSP94 during capacitation: the absence of ESP13.2 is linked to sperm-zona recognition and binding

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

The beta-defensin-fold family of polypeptides

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Novel antimicrobial peptide of human epididymal duct origin

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Testis-specific expression of a novel mouse defensin-like gene, Tdl.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Computational inference of homologous gene structures in the human genome

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Antibacterial properties of the sperm-binding proteins and peptides of human epididymis 2 (HE2) family; salt sensitivity, structural dependence and their interaction with outer and cytoplasmic membranes of Escherichia coli

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Antimicrobial actions of the human epididymis 2 (HE2) protein isoforms, HE2alpha, HE2beta1 and HE2beta2

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

The androgen-regulated epididymal sperm-binding protein, human beta-defensin 118 (DEFB118) (formerly ESC42), is an antimicrobial beta-defensin.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

ESP13.2, a member of the beta-defensin family, is a macaque sperm surface-coating protein involved in the capacitation process

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Identification on mouse chromosome 8 of new beta-defensin genes with regionally specific expression in the male reproductive organ.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Cathelicidins, multifunctional peptides of the innate immunity

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Secreted epididymal glycoprotein 2D6 that binds to the sperm's plasma membrane is a member of the beta-defensin superfamily of pore-forming glycopeptides

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

Cloning and characterization of the gene for a new epithelial beta-defensin. Genomic structure, chromosomal localization, and evidence for its constitutive expression

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

An epididymis-specific beta-defensin is important for the initiation of sperm maturation

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00104.2005

21 January 2018

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10.1152/PHYSIOLGENOMICS.00104.2005

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