(Q28266168)

2

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Bhupendra Rawal

3

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Y Ann Chen

4

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Harshani R Lawrence

5

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Robert W Engelman

6

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Nicholas J Lawrence

7

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Nupam P Mahajan

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

22 June 2012

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published in

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volume

287

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page(s)

22112-22

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issue

26

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cites work

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PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics

20 March 2017

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Shepherding AKT and androgen receptor by Ack1 tyrosine kinase

20 March 2017

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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation

20 March 2017

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The DNA-damage response in human biology and disease

20 March 2017

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DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture

20 March 2017

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

20 March 2017

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Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

20 March 2017

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

20 March 2017

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Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox

20 March 2017

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

20 March 2017

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Molecular determinants of resistance to antiandrogen therapy

20 March 2017

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Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck

20 March 2017

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Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase

20 March 2017

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

20 March 2017

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A single ataxia telangiectasia gene with a product similar to PI-3 kinase

20 March 2017

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

7 April 2017

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Integrative genomic profiling of human prostate cancer

7 April 2017

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Low levels of ATM in breast cancer patients with clinical radiosensitivity

7 April 2017

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Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity.

29 September 2017

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Castration-resistant prostate cancer: current and emerging treatment strategies

29 September 2017

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Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.

29 September 2017

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Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer

29 September 2017

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Castration-resistant prostate cancer: locking up the molecular escape routes

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Targeting the androgen receptor pathway in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

A chemical method for fast and sensitive detection of DNA synthesis in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

DNA damage checkpoints: from initiation to recovery or adaptation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

G2 checkpoint abrogators as anticancer drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

ATM--a key determinant of multiple cellular responses to irradiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

ATM is a target for positive regulation by E2F-1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3381169

ATM sequence variants are predictive of adverse radiotherapy response among patients treated for prostate cancer.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.357384

Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SAR.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112.357384

Sequence Variant Discovery in DNA Repair Genes from Radiosensitive and Radiotolerant Prostate Brachytherapy Patients

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M112.357384